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1R6G

Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues16
DetailsBINDING SITE FOR RESIDUE 442 A 500
ChainResidue
APHE272
AGLY345
ALEU346
AHIS435
AARG438
APHE439
AMET442
APHE455
AILE276
AALA279
AARG282
AMET313
AARG320
ALEU330
AASN331
AGLY344

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"15466465","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Y0X","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247947

PDB entries from 2026-01-21

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