1R0L

1-deoxy-D-xylulose 5-phosphate reductoisomerase from zymomonas mobilis in complex with NADPH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A	0030145	molecular_function	manganese ion binding
A	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A	0046872	molecular_function	metal ion binding
A	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
A	0070402	molecular_function	NADPH binding
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
B	0030145	molecular_function	manganese ion binding
B	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B	0046872	molecular_function	metal ion binding
B	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
B	0070402	molecular_function	NADPH binding
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
C	0030145	molecular_function	manganese ion binding
C	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C	0046872	molecular_function	metal ion binding
C	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
C	0070402	molecular_function	NADPH binding
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
D	0030145	molecular_function	manganese ion binding
D	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D	0046872	molecular_function	metal ion binding
D	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
D	0070402	molecular_function	NADPH binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NDP A 400

Chain	Residue
A	GLY11
A	THR13
A	GLY14
A	ASN39
A	ARG40
A	ASN41
A	ILE101
A	ALA105
A	HOH430

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NDP B 401

Chain	Residue
B	GLY11
B	ALA12
B	THR13
B	GLY14
B	ASN39
B	ARG40
B	ASN41
B	ALA60
B	ILE101

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE NDP C 402

Chain	Residue
C	GLY11
C	THR13
C	GLY14
C	ALA38
C	ASN39
C	ARG40
C	ASN41
C	ILE101
C	ALA105
C	HOH424

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NDP D 403

Chain	Residue
D	GLY11
D	THR13
D	GLY14
D	ALA38
D	ASN39
D	ARG40
D	ASN41
D	ALA60
D	LEU86
D	ILE102
D	ALA105
D	HOH423

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	71
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00183","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---