1R0K

Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Zymomonas mobilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A	0030145	molecular_function	manganese ion binding
A	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A	0046872	molecular_function	metal ion binding
A	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
A	0070402	molecular_function	NADPH binding
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
B	0030145	molecular_function	manganese ion binding
B	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B	0046872	molecular_function	metal ion binding
B	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
B	0070402	molecular_function	NADPH binding
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
C	0030145	molecular_function	manganese ion binding
C	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C	0046872	molecular_function	metal ion binding
C	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
C	0070402	molecular_function	NADPH binding
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
D	0030145	molecular_function	manganese ion binding
D	0030604	molecular_function	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D	0046872	molecular_function	metal ion binding
D	0051484	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
D	0070402	molecular_function	NADPH binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 1301

Chain	Residue
A	THR13
A	ASN39
A	ARG40
A	ASN41
A	HOH1356
A	HOH1493

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT B 1302

Chain	Residue
B	ARG40
B	ASN41
B	THR13
B	ALA38
B	ASN39

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT C 1303

Chain	Residue
C	THR13
C	ASN39
C	ARG40
C	ASN41

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT D 1304

Chain	Residue
D	THR13
D	ASN39
D	ARG40
D	ASN41
D	HOH1306
D	HOH1544

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	74
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00183","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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