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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

1QX7

Crystal structure of apoCaM bound to the gating domain of small conductance Ca2+-activated potassium channel

Functional Information from GO Data
ChainGOidnamespacecontents
A0000086biological_processG2/M transition of mitotic cell cycle
A0000785cellular_componentchromatin
A0000922cellular_componentspindle pole
A0001975biological_processresponse to amphetamine
A0002027biological_processregulation of heart rate
A0005246molecular_functioncalcium channel regulator activity
A0005509molecular_functioncalcium ion binding
A0005513biological_processdetection of calcium ion
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005813cellular_componentcentrosome
A0005819cellular_componentspindle
A0005829cellular_componentcytosol
A0005876cellular_componentspindle microtubule
A0007259biological_processcell surface receptor signaling pathway via JAK-STAT
A0008076cellular_componentvoltage-gated potassium channel complex
A0008179molecular_functionadenylate cyclase binding
A0010856molecular_functionadenylate cyclase activator activity
A0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A0016020cellular_componentmembrane
A0016240biological_processautophagosome membrane docking
A0019855molecular_functioncalcium channel inhibitor activity
A0019901molecular_functionprotein kinase binding
A0019904molecular_functionprotein domain specific binding
A0030017cellular_componentsarcomere
A0030235molecular_functionnitric-oxide synthase regulator activity
A0030426cellular_componentgrowth cone
A0030672cellular_componentsynaptic vesicle membrane
A0031432molecular_functiontitin binding
A0031514cellular_componentmotile cilium
A0031800molecular_functiontype 3 metabotropic glutamate receptor binding
A0031966cellular_componentmitochondrial membrane
A0031982cellular_componentvesicle
A0032465biological_processregulation of cytokinesis
A0032991cellular_componentprotein-containing complex
A0034704cellular_componentcalcium channel complex
A0035458biological_processcellular response to interferon-beta
A0043209cellular_componentmyelin sheath
A0043539molecular_functionprotein serine/threonine kinase activator activity
A0043548molecular_functionphosphatidylinositol 3-kinase binding
A0044305cellular_componentcalyx of Held
A0044325molecular_functiontransmembrane transporter binding
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0046872molecular_functionmetal ion binding
A0048306molecular_functioncalcium-dependent protein binding
A0050848biological_processregulation of calcium-mediated signaling
A0050998molecular_functionnitric-oxide synthase binding
A0051412biological_processresponse to corticosterone
A0051592biological_processresponse to calcium ion
A0055117biological_processregulation of cardiac muscle contraction
A0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
A0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
A0071346biological_processcellular response to type II interferon
A0072542molecular_functionprotein phosphatase activator activity
A0090150biological_processestablishment of protein localization to membrane
A0090151biological_processestablishment of protein localization to mitochondrial membrane
A0097225cellular_componentsperm midpiece
A0097720biological_processcalcineurin-mediated signaling
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098901biological_processregulation of cardiac muscle cell action potential
A0099523cellular_componentpresynaptic cytosol
A0099524cellular_componentpostsynaptic cytosol
A0140056biological_processorganelle localization by membrane tethering
A0140238biological_processpresynaptic endocytosis
A0141110molecular_functiontransporter inhibitor activity
A1900242biological_processregulation of synaptic vesicle endocytosis
A1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
A1902494cellular_componentcatalytic complex
A1905913biological_processnegative regulation of calcium ion export across plasma membrane
A1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
A2000300biological_processregulation of synaptic vesicle exocytosis
B0000086biological_processG2/M transition of mitotic cell cycle
B0000785cellular_componentchromatin
B0000922cellular_componentspindle pole
B0001975biological_processresponse to amphetamine
B0002027biological_processregulation of heart rate
B0005246molecular_functioncalcium channel regulator activity
B0005509molecular_functioncalcium ion binding
B0005513biological_processdetection of calcium ion
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005876cellular_componentspindle microtubule
B0007259biological_processcell surface receptor signaling pathway via JAK-STAT
B0008076cellular_componentvoltage-gated potassium channel complex
B0008179molecular_functionadenylate cyclase binding
B0010856molecular_functionadenylate cyclase activator activity
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0016020cellular_componentmembrane
B0016240biological_processautophagosome membrane docking
B0019855molecular_functioncalcium channel inhibitor activity
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0030017cellular_componentsarcomere
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031432molecular_functiontitin binding
B0031514cellular_componentmotile cilium
B0031800molecular_functiontype 3 metabotropic glutamate receptor binding
B0031966cellular_componentmitochondrial membrane
B0031982cellular_componentvesicle
B0032465biological_processregulation of cytokinesis
B0032991cellular_componentprotein-containing complex
B0034704cellular_componentcalcium channel complex
B0035458biological_processcellular response to interferon-beta
B0043209cellular_componentmyelin sheath
B0043539molecular_functionprotein serine/threonine kinase activator activity
B0043548molecular_functionphosphatidylinositol 3-kinase binding
B0044305cellular_componentcalyx of Held
B0044325molecular_functiontransmembrane transporter binding
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046872molecular_functionmetal ion binding
B0048306molecular_functioncalcium-dependent protein binding
B0050848biological_processregulation of calcium-mediated signaling
B0050998molecular_functionnitric-oxide synthase binding
B0051412biological_processresponse to corticosterone
B0051592biological_processresponse to calcium ion
B0055117biological_processregulation of cardiac muscle contraction
B0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
B0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
B0071346biological_processcellular response to type II interferon
B0072542molecular_functionprotein phosphatase activator activity
B0090150biological_processestablishment of protein localization to membrane
B0090151biological_processestablishment of protein localization to mitochondrial membrane
B0097225cellular_componentsperm midpiece
B0097720biological_processcalcineurin-mediated signaling
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098901biological_processregulation of cardiac muscle cell action potential
B0099523cellular_componentpresynaptic cytosol
B0099524cellular_componentpostsynaptic cytosol
B0140056biological_processorganelle localization by membrane tethering
B0140238biological_processpresynaptic endocytosis
B0141110molecular_functiontransporter inhibitor activity
B1900242biological_processregulation of synaptic vesicle endocytosis
B1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
B1902494cellular_componentcatalytic complex
B1905913biological_processnegative regulation of calcium ion export across plasma membrane
B1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
B2000300biological_processregulation of synaptic vesicle exocytosis
D0005516molecular_functioncalmodulin binding
D0006813biological_processpotassium ion transport
D0015269molecular_functioncalcium-activated potassium channel activity
D0016020cellular_componentmembrane
D0016286molecular_functionsmall conductance calcium-activated potassium channel activity
I0000086biological_processG2/M transition of mitotic cell cycle
I0000785cellular_componentchromatin
I0000922cellular_componentspindle pole
I0001975biological_processresponse to amphetamine
I0002027biological_processregulation of heart rate
I0005246molecular_functioncalcium channel regulator activity
I0005509molecular_functioncalcium ion binding
I0005513biological_processdetection of calcium ion
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005813cellular_componentcentrosome
I0005819cellular_componentspindle
I0005829cellular_componentcytosol
I0005876cellular_componentspindle microtubule
I0007259biological_processcell surface receptor signaling pathway via JAK-STAT
I0008076cellular_componentvoltage-gated potassium channel complex
I0008179molecular_functionadenylate cyclase binding
I0010856molecular_functionadenylate cyclase activator activity
I0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
I0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
I0016020cellular_componentmembrane
I0016240biological_processautophagosome membrane docking
I0019855molecular_functioncalcium channel inhibitor activity
I0019901molecular_functionprotein kinase binding
I0019904molecular_functionprotein domain specific binding
I0030017cellular_componentsarcomere
I0030235molecular_functionnitric-oxide synthase regulator activity
I0030426cellular_componentgrowth cone
I0030672cellular_componentsynaptic vesicle membrane
I0031432molecular_functiontitin binding
I0031514cellular_componentmotile cilium
I0031800molecular_functiontype 3 metabotropic glutamate receptor binding
I0031966cellular_componentmitochondrial membrane
I0031982cellular_componentvesicle
I0032465biological_processregulation of cytokinesis
I0032991cellular_componentprotein-containing complex
I0034704cellular_componentcalcium channel complex
I0035458biological_processcellular response to interferon-beta
I0043209cellular_componentmyelin sheath
I0043539molecular_functionprotein serine/threonine kinase activator activity
I0043548molecular_functionphosphatidylinositol 3-kinase binding
I0044305cellular_componentcalyx of Held
I0044325molecular_functiontransmembrane transporter binding
I0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
I0046872molecular_functionmetal ion binding
I0048306molecular_functioncalcium-dependent protein binding
I0050848biological_processregulation of calcium-mediated signaling
I0050998molecular_functionnitric-oxide synthase binding
I0051412biological_processresponse to corticosterone
I0051592biological_processresponse to calcium ion
I0055117biological_processregulation of cardiac muscle contraction
I0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
I0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
I0071346biological_processcellular response to type II interferon
I0072542molecular_functionprotein phosphatase activator activity
I0090150biological_processestablishment of protein localization to membrane
I0090151biological_processestablishment of protein localization to mitochondrial membrane
I0097225cellular_componentsperm midpiece
I0097720biological_processcalcineurin-mediated signaling
I0098685cellular_componentSchaffer collateral - CA1 synapse
I0098901biological_processregulation of cardiac muscle cell action potential
I0099523cellular_componentpresynaptic cytosol
I0099524cellular_componentpostsynaptic cytosol
I0140056biological_processorganelle localization by membrane tethering
I0140238biological_processpresynaptic endocytosis
I0141110molecular_functiontransporter inhibitor activity
I1900242biological_processregulation of synaptic vesicle endocytosis
I1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
I1902494cellular_componentcatalytic complex
I1905913biological_processnegative regulation of calcium ion export across plasma membrane
I1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
I2000300biological_processregulation of synaptic vesicle exocytosis
M0000086biological_processG2/M transition of mitotic cell cycle
M0000785cellular_componentchromatin
M0000922cellular_componentspindle pole
M0001975biological_processresponse to amphetamine
M0002027biological_processregulation of heart rate
M0005246molecular_functioncalcium channel regulator activity
M0005509molecular_functioncalcium ion binding
M0005513biological_processdetection of calcium ion
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005813cellular_componentcentrosome
M0005819cellular_componentspindle
M0005829cellular_componentcytosol
M0005876cellular_componentspindle microtubule
M0007259biological_processcell surface receptor signaling pathway via JAK-STAT
M0008076cellular_componentvoltage-gated potassium channel complex
M0008179molecular_functionadenylate cyclase binding
M0010856molecular_functionadenylate cyclase activator activity
M0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
M0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
M0016020cellular_componentmembrane
M0016240biological_processautophagosome membrane docking
M0019855molecular_functioncalcium channel inhibitor activity
M0019901molecular_functionprotein kinase binding
M0019904molecular_functionprotein domain specific binding
M0030017cellular_componentsarcomere
M0030235molecular_functionnitric-oxide synthase regulator activity
M0030426cellular_componentgrowth cone
M0030672cellular_componentsynaptic vesicle membrane
M0031432molecular_functiontitin binding
M0031514cellular_componentmotile cilium
M0031800molecular_functiontype 3 metabotropic glutamate receptor binding
M0031966cellular_componentmitochondrial membrane
M0031982cellular_componentvesicle
M0032465biological_processregulation of cytokinesis
M0032991cellular_componentprotein-containing complex
M0034704cellular_componentcalcium channel complex
M0035458biological_processcellular response to interferon-beta
M0043209cellular_componentmyelin sheath
M0043539molecular_functionprotein serine/threonine kinase activator activity
M0043548molecular_functionphosphatidylinositol 3-kinase binding
M0044305cellular_componentcalyx of Held
M0044325molecular_functiontransmembrane transporter binding
M0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
M0046872molecular_functionmetal ion binding
M0048306molecular_functioncalcium-dependent protein binding
M0050848biological_processregulation of calcium-mediated signaling
M0050998molecular_functionnitric-oxide synthase binding
M0051412biological_processresponse to corticosterone
M0051592biological_processresponse to calcium ion
M0055117biological_processregulation of cardiac muscle contraction
M0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
M0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
M0071346biological_processcellular response to type II interferon
M0072542molecular_functionprotein phosphatase activator activity
M0090150biological_processestablishment of protein localization to membrane
M0090151biological_processestablishment of protein localization to mitochondrial membrane
M0097225cellular_componentsperm midpiece
M0097720biological_processcalcineurin-mediated signaling
M0098685cellular_componentSchaffer collateral - CA1 synapse
M0098901biological_processregulation of cardiac muscle cell action potential
M0099523cellular_componentpresynaptic cytosol
M0099524cellular_componentpostsynaptic cytosol
M0140056biological_processorganelle localization by membrane tethering
M0140238biological_processpresynaptic endocytosis
M0141110molecular_functiontransporter inhibitor activity
M1900242biological_processregulation of synaptic vesicle endocytosis
M1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
M1902494cellular_componentcatalytic complex
M1905913biological_processnegative regulation of calcium ion export across plasma membrane
M1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
M2000300biological_processregulation of synaptic vesicle exocytosis
R0000086biological_processG2/M transition of mitotic cell cycle
R0000785cellular_componentchromatin
R0000922cellular_componentspindle pole
R0001975biological_processresponse to amphetamine
R0002027biological_processregulation of heart rate
R0005246molecular_functioncalcium channel regulator activity
R0005509molecular_functioncalcium ion binding
R0005513biological_processdetection of calcium ion
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005654cellular_componentnucleoplasm
R0005737cellular_componentcytoplasm
R0005739cellular_componentmitochondrion
R0005813cellular_componentcentrosome
R0005819cellular_componentspindle
R0005829cellular_componentcytosol
R0005876cellular_componentspindle microtubule
R0007259biological_processcell surface receptor signaling pathway via JAK-STAT
R0008076cellular_componentvoltage-gated potassium channel complex
R0008179molecular_functionadenylate cyclase binding
R0010856molecular_functionadenylate cyclase activator activity
R0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
R0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
R0016020cellular_componentmembrane
R0016240biological_processautophagosome membrane docking
R0019855molecular_functioncalcium channel inhibitor activity
R0019901molecular_functionprotein kinase binding
R0019904molecular_functionprotein domain specific binding
R0030017cellular_componentsarcomere
R0030235molecular_functionnitric-oxide synthase regulator activity
R0030426cellular_componentgrowth cone
R0030672cellular_componentsynaptic vesicle membrane
R0031432molecular_functiontitin binding
R0031514cellular_componentmotile cilium
R0031800molecular_functiontype 3 metabotropic glutamate receptor binding
R0031966cellular_componentmitochondrial membrane
R0031982cellular_componentvesicle
R0032465biological_processregulation of cytokinesis
R0032991cellular_componentprotein-containing complex
R0034704cellular_componentcalcium channel complex
R0035458biological_processcellular response to interferon-beta
R0043209cellular_componentmyelin sheath
R0043539molecular_functionprotein serine/threonine kinase activator activity
R0043548molecular_functionphosphatidylinositol 3-kinase binding
R0044305cellular_componentcalyx of Held
R0044325molecular_functiontransmembrane transporter binding
R0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
R0046872molecular_functionmetal ion binding
R0048306molecular_functioncalcium-dependent protein binding
R0050848biological_processregulation of calcium-mediated signaling
R0050998molecular_functionnitric-oxide synthase binding
R0051412biological_processresponse to corticosterone
R0051592biological_processresponse to calcium ion
R0055117biological_processregulation of cardiac muscle contraction
R0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
R0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
R0071346biological_processcellular response to type II interferon
R0072542molecular_functionprotein phosphatase activator activity
R0090150biological_processestablishment of protein localization to membrane
R0090151biological_processestablishment of protein localization to mitochondrial membrane
R0097225cellular_componentsperm midpiece
R0097720biological_processcalcineurin-mediated signaling
R0098685cellular_componentSchaffer collateral - CA1 synapse
R0098901biological_processregulation of cardiac muscle cell action potential
R0099523cellular_componentpresynaptic cytosol
R0099524cellular_componentpostsynaptic cytosol
R0140056biological_processorganelle localization by membrane tethering
R0140238biological_processpresynaptic endocytosis
R0141110molecular_functiontransporter inhibitor activity
R1900242biological_processregulation of synaptic vesicle endocytosis
R1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
R1902494cellular_componentcatalytic complex
R1905913biological_processnegative regulation of calcium ion export across plasma membrane
R1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
R2000300biological_processregulation of synaptic vesicle exocytosis
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL
ChainResidueDetails
IASP20-LEU32
IASP56-PHE68
IASP93-LEU105
IASP129-PHE141
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues22
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11323678","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23109337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3145979","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1G4Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HQW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YGG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B32","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4G27","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4G28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4J9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4J9Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QNH","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11323678","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23109337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3145979","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1G4Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HQW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YGG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B32","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EVR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WLC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4G27","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4G28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4J9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4J9Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QNH","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23109337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3145979","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HQW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YGG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EVR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SG7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WLC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RJD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues4
DetailsModified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues5
DetailsModified residue: {"description":"Phosphothreonine; by CaMK4","evidences":[{"source":"PubMed","id":"12392717","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues5
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues4
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues5
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues5
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues5
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues5
DetailsModified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues8
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62157","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues1
DetailsModified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"201628","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2007","submissionDatabase":"UniProtKB","authors":["Lubec G.","Chen W.-Q."]}}]}
ChainResidueDetails

245011

PDB entries from 2025-11-19

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