1QX5

Crystal structure of apoCalmodulin

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000086	biological_process	G2/M transition of mitotic cell cycle
B	0000922	cellular_component	spindle pole
B	0001975	biological_process	response to amphetamine
B	0002027	biological_process	regulation of heart rate
B	0005246	molecular_function	calcium channel regulator activity
B	0005509	molecular_function	calcium ion binding
B	0005513	biological_process	detection of calcium ion
B	0005515	molecular_function	protein binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005813	cellular_component	centrosome
B	0005819	cellular_component	spindle
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005876	cellular_component	spindle microtubule
B	0005929	cellular_component	cilium
B	0008076	cellular_component	voltage-gated potassium channel complex
B	0008179	molecular_function	adenylate cyclase binding
B	0010856	molecular_function	adenylate cyclase activator activity
B	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B	0016240	biological_process	autophagosome membrane docking
B	0019855	molecular_function	calcium channel inhibitor activity
B	0019901	molecular_function	protein kinase binding
B	0019904	molecular_function	protein domain specific binding
B	0030017	cellular_component	sarcomere
B	0030234	molecular_function	enzyme regulator activity
B	0030235	molecular_function	nitric-oxide synthase regulator activity
B	0030426	cellular_component	growth cone
B	0030672	cellular_component	synaptic vesicle membrane
B	0031432	molecular_function	titin binding
B	0031514	cellular_component	motile cilium
B	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
B	0031966	cellular_component	mitochondrial membrane
B	0032465	biological_process	regulation of cytokinesis
B	0032991	cellular_component	protein-containing complex
B	0034704	cellular_component	calcium channel complex
B	0035307	biological_process	positive regulation of protein dephosphorylation
B	0035458	biological_process	cellular response to interferon-beta
B	0042995	cellular_component	cell projection
B	0043209	cellular_component	myelin sheath
B	0043539	molecular_function	protein serine/threonine kinase activator activity
B	0043548	molecular_function	phosphatidylinositol 3-kinase binding
B	0044325	molecular_function	transmembrane transporter binding
B	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
B	0046872	molecular_function	metal ion binding
B	0048306	molecular_function	calcium-dependent protein binding
B	0050998	molecular_function	nitric-oxide synthase binding
B	0051592	biological_process	response to calcium ion
B	0055117	biological_process	regulation of cardiac muscle contraction
B	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
B	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
B	0071346	biological_process	cellular response to type II interferon
B	0072542	molecular_function	protein phosphatase activator activity
B	0090150	biological_process	establishment of protein localization to membrane
B	0090151	biological_process	establishment of protein localization to mitochondrial membrane
B	0097225	cellular_component	sperm midpiece
B	0098901	biological_process	regulation of cardiac muscle cell action potential
B	0140056	biological_process	organelle localization by membrane tethering
B	1900242	biological_process	regulation of synaptic vesicle endocytosis
B	1902494	cellular_component	catalytic complex
B	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
B	2000300	biological_process	regulation of synaptic vesicle exocytosis
D	0000086	biological_process	G2/M transition of mitotic cell cycle
D	0000922	cellular_component	spindle pole
D	0001975	biological_process	response to amphetamine
D	0002027	biological_process	regulation of heart rate
D	0005246	molecular_function	calcium channel regulator activity
D	0005509	molecular_function	calcium ion binding
D	0005513	biological_process	detection of calcium ion
D	0005515	molecular_function	protein binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005813	cellular_component	centrosome
D	0005819	cellular_component	spindle
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005876	cellular_component	spindle microtubule
D	0005929	cellular_component	cilium
D	0008076	cellular_component	voltage-gated potassium channel complex
D	0008179	molecular_function	adenylate cyclase binding
D	0010856	molecular_function	adenylate cyclase activator activity
D	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D	0016240	biological_process	autophagosome membrane docking
D	0019855	molecular_function	calcium channel inhibitor activity
D	0019901	molecular_function	protein kinase binding
D	0019904	molecular_function	protein domain specific binding
D	0030017	cellular_component	sarcomere
D	0030234	molecular_function	enzyme regulator activity
D	0030235	molecular_function	nitric-oxide synthase regulator activity
D	0030426	cellular_component	growth cone
D	0030672	cellular_component	synaptic vesicle membrane
D	0031432	molecular_function	titin binding
D	0031514	cellular_component	motile cilium
D	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
D	0031966	cellular_component	mitochondrial membrane
D	0032465	biological_process	regulation of cytokinesis
D	0032991	cellular_component	protein-containing complex
D	0034704	cellular_component	calcium channel complex
D	0035307	biological_process	positive regulation of protein dephosphorylation
D	0035458	biological_process	cellular response to interferon-beta
D	0042995	cellular_component	cell projection
D	0043209	cellular_component	myelin sheath
D	0043539	molecular_function	protein serine/threonine kinase activator activity
D	0043548	molecular_function	phosphatidylinositol 3-kinase binding
D	0044325	molecular_function	transmembrane transporter binding
D	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
D	0046872	molecular_function	metal ion binding
D	0048306	molecular_function	calcium-dependent protein binding
D	0050998	molecular_function	nitric-oxide synthase binding
D	0051592	biological_process	response to calcium ion
D	0055117	biological_process	regulation of cardiac muscle contraction
D	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
D	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
D	0071346	biological_process	cellular response to type II interferon
D	0072542	molecular_function	protein phosphatase activator activity
D	0090150	biological_process	establishment of protein localization to membrane
D	0090151	biological_process	establishment of protein localization to mitochondrial membrane
D	0097225	cellular_component	sperm midpiece
D	0098901	biological_process	regulation of cardiac muscle cell action potential
D	0140056	biological_process	organelle localization by membrane tethering
D	1900242	biological_process	regulation of synaptic vesicle endocytosis
D	1902494	cellular_component	catalytic complex
D	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
D	2000300	biological_process	regulation of synaptic vesicle exocytosis
I	0000086	biological_process	G2/M transition of mitotic cell cycle
I	0000922	cellular_component	spindle pole
I	0001975	biological_process	response to amphetamine
I	0002027	biological_process	regulation of heart rate
I	0005246	molecular_function	calcium channel regulator activity
I	0005509	molecular_function	calcium ion binding
I	0005513	biological_process	detection of calcium ion
I	0005515	molecular_function	protein binding
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005813	cellular_component	centrosome
I	0005819	cellular_component	spindle
I	0005829	cellular_component	cytosol
I	0005856	cellular_component	cytoskeleton
I	0005876	cellular_component	spindle microtubule
I	0005929	cellular_component	cilium
I	0008076	cellular_component	voltage-gated potassium channel complex
I	0008179	molecular_function	adenylate cyclase binding
I	0010856	molecular_function	adenylate cyclase activator activity
I	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
I	0016240	biological_process	autophagosome membrane docking
I	0019855	molecular_function	calcium channel inhibitor activity
I	0019901	molecular_function	protein kinase binding
I	0019904	molecular_function	protein domain specific binding
I	0030017	cellular_component	sarcomere
I	0030234	molecular_function	enzyme regulator activity
I	0030235	molecular_function	nitric-oxide synthase regulator activity
I	0030426	cellular_component	growth cone
I	0030672	cellular_component	synaptic vesicle membrane
I	0031432	molecular_function	titin binding
I	0031514	cellular_component	motile cilium
I	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
I	0031966	cellular_component	mitochondrial membrane
I	0032465	biological_process	regulation of cytokinesis
I	0032991	cellular_component	protein-containing complex
I	0034704	cellular_component	calcium channel complex
I	0035307	biological_process	positive regulation of protein dephosphorylation
I	0035458	biological_process	cellular response to interferon-beta
I	0042995	cellular_component	cell projection
I	0043209	cellular_component	myelin sheath
I	0043539	molecular_function	protein serine/threonine kinase activator activity
I	0043548	molecular_function	phosphatidylinositol 3-kinase binding
I	0044325	molecular_function	transmembrane transporter binding
I	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
I	0046872	molecular_function	metal ion binding
I	0048306	molecular_function	calcium-dependent protein binding
I	0050998	molecular_function	nitric-oxide synthase binding
I	0051592	biological_process	response to calcium ion
I	0055117	biological_process	regulation of cardiac muscle contraction
I	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
I	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
I	0071346	biological_process	cellular response to type II interferon
I	0072542	molecular_function	protein phosphatase activator activity
I	0090150	biological_process	establishment of protein localization to membrane
I	0090151	biological_process	establishment of protein localization to mitochondrial membrane
I	0097225	cellular_component	sperm midpiece
I	0098901	biological_process	regulation of cardiac muscle cell action potential
I	0140056	biological_process	organelle localization by membrane tethering
I	1900242	biological_process	regulation of synaptic vesicle endocytosis
I	1902494	cellular_component	catalytic complex
I	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
I	2000300	biological_process	regulation of synaptic vesicle exocytosis
J	0000086	biological_process	G2/M transition of mitotic cell cycle
J	0000922	cellular_component	spindle pole
J	0001975	biological_process	response to amphetamine
J	0002027	biological_process	regulation of heart rate
J	0005246	molecular_function	calcium channel regulator activity
J	0005509	molecular_function	calcium ion binding
J	0005513	biological_process	detection of calcium ion
J	0005515	molecular_function	protein binding
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005813	cellular_component	centrosome
J	0005819	cellular_component	spindle
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0005876	cellular_component	spindle microtubule
J	0005929	cellular_component	cilium
J	0008076	cellular_component	voltage-gated potassium channel complex
J	0008179	molecular_function	adenylate cyclase binding
J	0010856	molecular_function	adenylate cyclase activator activity
J	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
J	0016240	biological_process	autophagosome membrane docking
J	0019855	molecular_function	calcium channel inhibitor activity
J	0019901	molecular_function	protein kinase binding
J	0019904	molecular_function	protein domain specific binding
J	0030017	cellular_component	sarcomere
J	0030234	molecular_function	enzyme regulator activity
J	0030235	molecular_function	nitric-oxide synthase regulator activity
J	0030426	cellular_component	growth cone
J	0030672	cellular_component	synaptic vesicle membrane
J	0031432	molecular_function	titin binding
J	0031514	cellular_component	motile cilium
J	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
J	0031966	cellular_component	mitochondrial membrane
J	0032465	biological_process	regulation of cytokinesis
J	0032991	cellular_component	protein-containing complex
J	0034704	cellular_component	calcium channel complex
J	0035307	biological_process	positive regulation of protein dephosphorylation
J	0035458	biological_process	cellular response to interferon-beta
J	0042995	cellular_component	cell projection
J	0043209	cellular_component	myelin sheath
J	0043539	molecular_function	protein serine/threonine kinase activator activity
J	0043548	molecular_function	phosphatidylinositol 3-kinase binding
J	0044325	molecular_function	transmembrane transporter binding
J	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
J	0046872	molecular_function	metal ion binding
J	0048306	molecular_function	calcium-dependent protein binding
J	0050998	molecular_function	nitric-oxide synthase binding
J	0051592	biological_process	response to calcium ion
J	0055117	biological_process	regulation of cardiac muscle contraction
J	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
J	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
J	0071346	biological_process	cellular response to type II interferon
J	0072542	molecular_function	protein phosphatase activator activity
J	0090150	biological_process	establishment of protein localization to membrane
J	0090151	biological_process	establishment of protein localization to mitochondrial membrane
J	0097225	cellular_component	sperm midpiece
J	0098901	biological_process	regulation of cardiac muscle cell action potential
J	0140056	biological_process	organelle localization by membrane tethering
J	1900242	biological_process	regulation of synaptic vesicle endocytosis
J	1902494	cellular_component	catalytic complex
J	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
J	2000300	biological_process	regulation of synaptic vesicle exocytosis
K	0000086	biological_process	G2/M transition of mitotic cell cycle
K	0000922	cellular_component	spindle pole
K	0001975	biological_process	response to amphetamine
K	0002027	biological_process	regulation of heart rate
K	0005246	molecular_function	calcium channel regulator activity
K	0005509	molecular_function	calcium ion binding
K	0005513	biological_process	detection of calcium ion
K	0005515	molecular_function	protein binding
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005813	cellular_component	centrosome
K	0005819	cellular_component	spindle
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0005876	cellular_component	spindle microtubule
K	0005929	cellular_component	cilium
K	0008076	cellular_component	voltage-gated potassium channel complex
K	0008179	molecular_function	adenylate cyclase binding
K	0010856	molecular_function	adenylate cyclase activator activity
K	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
K	0016240	biological_process	autophagosome membrane docking
K	0019855	molecular_function	calcium channel inhibitor activity
K	0019901	molecular_function	protein kinase binding
K	0019904	molecular_function	protein domain specific binding
K	0030017	cellular_component	sarcomere
K	0030234	molecular_function	enzyme regulator activity
K	0030235	molecular_function	nitric-oxide synthase regulator activity
K	0030426	cellular_component	growth cone
K	0030672	cellular_component	synaptic vesicle membrane
K	0031432	molecular_function	titin binding
K	0031514	cellular_component	motile cilium
K	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
K	0031966	cellular_component	mitochondrial membrane
K	0032465	biological_process	regulation of cytokinesis
K	0032991	cellular_component	protein-containing complex
K	0034704	cellular_component	calcium channel complex
K	0035307	biological_process	positive regulation of protein dephosphorylation
K	0035458	biological_process	cellular response to interferon-beta
K	0042995	cellular_component	cell projection
K	0043209	cellular_component	myelin sheath
K	0043539	molecular_function	protein serine/threonine kinase activator activity
K	0043548	molecular_function	phosphatidylinositol 3-kinase binding
K	0044325	molecular_function	transmembrane transporter binding
K	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
K	0046872	molecular_function	metal ion binding
K	0048306	molecular_function	calcium-dependent protein binding
K	0050998	molecular_function	nitric-oxide synthase binding
K	0051592	biological_process	response to calcium ion
K	0055117	biological_process	regulation of cardiac muscle contraction
K	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
K	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
K	0071346	biological_process	cellular response to type II interferon
K	0072542	molecular_function	protein phosphatase activator activity
K	0090150	biological_process	establishment of protein localization to membrane
K	0090151	biological_process	establishment of protein localization to mitochondrial membrane
K	0097225	cellular_component	sperm midpiece
K	0098901	biological_process	regulation of cardiac muscle cell action potential
K	0140056	biological_process	organelle localization by membrane tethering
K	1900242	biological_process	regulation of synaptic vesicle endocytosis
K	1902494	cellular_component	catalytic complex
K	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
K	2000300	biological_process	regulation of synaptic vesicle exocytosis
R	0000086	biological_process	G2/M transition of mitotic cell cycle
R	0000922	cellular_component	spindle pole
R	0001975	biological_process	response to amphetamine
R	0002027	biological_process	regulation of heart rate
R	0005246	molecular_function	calcium channel regulator activity
R	0005509	molecular_function	calcium ion binding
R	0005513	biological_process	detection of calcium ion
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005813	cellular_component	centrosome
R	0005819	cellular_component	spindle
R	0005829	cellular_component	cytosol
R	0005856	cellular_component	cytoskeleton
R	0005876	cellular_component	spindle microtubule
R	0005929	cellular_component	cilium
R	0008076	cellular_component	voltage-gated potassium channel complex
R	0008179	molecular_function	adenylate cyclase binding
R	0010856	molecular_function	adenylate cyclase activator activity
R	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
R	0016240	biological_process	autophagosome membrane docking
R	0019855	molecular_function	calcium channel inhibitor activity
R	0019901	molecular_function	protein kinase binding
R	0019904	molecular_function	protein domain specific binding
R	0030017	cellular_component	sarcomere
R	0030234	molecular_function	enzyme regulator activity
R	0030235	molecular_function	nitric-oxide synthase regulator activity
R	0030426	cellular_component	growth cone
R	0030672	cellular_component	synaptic vesicle membrane
R	0031432	molecular_function	titin binding
R	0031514	cellular_component	motile cilium
R	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
R	0031966	cellular_component	mitochondrial membrane
R	0032465	biological_process	regulation of cytokinesis
R	0032991	cellular_component	protein-containing complex
R	0034704	cellular_component	calcium channel complex
R	0035307	biological_process	positive regulation of protein dephosphorylation
R	0035458	biological_process	cellular response to interferon-beta
R	0042995	cellular_component	cell projection
R	0043209	cellular_component	myelin sheath
R	0043539	molecular_function	protein serine/threonine kinase activator activity
R	0043548	molecular_function	phosphatidylinositol 3-kinase binding
R	0044325	molecular_function	transmembrane transporter binding
R	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
R	0046872	molecular_function	metal ion binding
R	0048306	molecular_function	calcium-dependent protein binding
R	0050998	molecular_function	nitric-oxide synthase binding
R	0051592	biological_process	response to calcium ion
R	0055117	biological_process	regulation of cardiac muscle contraction
R	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
R	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
R	0071346	biological_process	cellular response to type II interferon
R	0072542	molecular_function	protein phosphatase activator activity
R	0090150	biological_process	establishment of protein localization to membrane
R	0090151	biological_process	establishment of protein localization to mitochondrial membrane
R	0097225	cellular_component	sperm midpiece
R	0098901	biological_process	regulation of cardiac muscle cell action potential
R	0140056	biological_process	organelle localization by membrane tethering
R	1900242	biological_process	regulation of synaptic vesicle endocytosis
R	1902494	cellular_component	catalytic complex
R	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
R	2000300	biological_process	regulation of synaptic vesicle exocytosis
T	0000086	biological_process	G2/M transition of mitotic cell cycle
T	0000922	cellular_component	spindle pole
T	0001975	biological_process	response to amphetamine
T	0002027	biological_process	regulation of heart rate
T	0005246	molecular_function	calcium channel regulator activity
T	0005509	molecular_function	calcium ion binding
T	0005513	biological_process	detection of calcium ion
T	0005515	molecular_function	protein binding
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005813	cellular_component	centrosome
T	0005819	cellular_component	spindle
T	0005829	cellular_component	cytosol
T	0005856	cellular_component	cytoskeleton
T	0005876	cellular_component	spindle microtubule
T	0005929	cellular_component	cilium
T	0008076	cellular_component	voltage-gated potassium channel complex
T	0008179	molecular_function	adenylate cyclase binding
T	0010856	molecular_function	adenylate cyclase activator activity
T	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
T	0016240	biological_process	autophagosome membrane docking
T	0019855	molecular_function	calcium channel inhibitor activity
T	0019901	molecular_function	protein kinase binding
T	0019904	molecular_function	protein domain specific binding
T	0030017	cellular_component	sarcomere
T	0030234	molecular_function	enzyme regulator activity
T	0030235	molecular_function	nitric-oxide synthase regulator activity
T	0030426	cellular_component	growth cone
T	0030672	cellular_component	synaptic vesicle membrane
T	0031432	molecular_function	titin binding
T	0031514	cellular_component	motile cilium
T	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
T	0031966	cellular_component	mitochondrial membrane
T	0032465	biological_process	regulation of cytokinesis
T	0032991	cellular_component	protein-containing complex
T	0034704	cellular_component	calcium channel complex
T	0035307	biological_process	positive regulation of protein dephosphorylation
T	0035458	biological_process	cellular response to interferon-beta
T	0042995	cellular_component	cell projection
T	0043209	cellular_component	myelin sheath
T	0043539	molecular_function	protein serine/threonine kinase activator activity
T	0043548	molecular_function	phosphatidylinositol 3-kinase binding
T	0044325	molecular_function	transmembrane transporter binding
T	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
T	0046872	molecular_function	metal ion binding
T	0048306	molecular_function	calcium-dependent protein binding
T	0050998	molecular_function	nitric-oxide synthase binding
T	0051592	biological_process	response to calcium ion
T	0055117	biological_process	regulation of cardiac muscle contraction
T	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
T	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
T	0071346	biological_process	cellular response to type II interferon
T	0072542	molecular_function	protein phosphatase activator activity
T	0090150	biological_process	establishment of protein localization to membrane
T	0090151	biological_process	establishment of protein localization to mitochondrial membrane
T	0097225	cellular_component	sperm midpiece
T	0098901	biological_process	regulation of cardiac muscle cell action potential
T	0140056	biological_process	organelle localization by membrane tethering
T	1900242	biological_process	regulation of synaptic vesicle endocytosis
T	1902494	cellular_component	catalytic complex
T	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
T	2000300	biological_process	regulation of synaptic vesicle exocytosis
Y	0000086	biological_process	G2/M transition of mitotic cell cycle
Y	0000922	cellular_component	spindle pole
Y	0001975	biological_process	response to amphetamine
Y	0002027	biological_process	regulation of heart rate
Y	0005246	molecular_function	calcium channel regulator activity
Y	0005509	molecular_function	calcium ion binding
Y	0005513	biological_process	detection of calcium ion
Y	0005515	molecular_function	protein binding
Y	0005654	cellular_component	nucleoplasm
Y	0005737	cellular_component	cytoplasm
Y	0005739	cellular_component	mitochondrion
Y	0005813	cellular_component	centrosome
Y	0005819	cellular_component	spindle
Y	0005829	cellular_component	cytosol
Y	0005856	cellular_component	cytoskeleton
Y	0005876	cellular_component	spindle microtubule
Y	0005929	cellular_component	cilium
Y	0008076	cellular_component	voltage-gated potassium channel complex
Y	0008179	molecular_function	adenylate cyclase binding
Y	0010856	molecular_function	adenylate cyclase activator activity
Y	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
Y	0016240	biological_process	autophagosome membrane docking
Y	0019855	molecular_function	calcium channel inhibitor activity
Y	0019901	molecular_function	protein kinase binding
Y	0019904	molecular_function	protein domain specific binding
Y	0030017	cellular_component	sarcomere
Y	0030234	molecular_function	enzyme regulator activity
Y	0030235	molecular_function	nitric-oxide synthase regulator activity
Y	0030426	cellular_component	growth cone
Y	0030672	cellular_component	synaptic vesicle membrane
Y	0031432	molecular_function	titin binding
Y	0031514	cellular_component	motile cilium
Y	0031800	molecular_function	type 3 metabotropic glutamate receptor binding
Y	0031966	cellular_component	mitochondrial membrane
Y	0032465	biological_process	regulation of cytokinesis
Y	0032991	cellular_component	protein-containing complex
Y	0034704	cellular_component	calcium channel complex
Y	0035307	biological_process	positive regulation of protein dephosphorylation
Y	0035458	biological_process	cellular response to interferon-beta
Y	0042995	cellular_component	cell projection
Y	0043209	cellular_component	myelin sheath
Y	0043539	molecular_function	protein serine/threonine kinase activator activity
Y	0043548	molecular_function	phosphatidylinositol 3-kinase binding
Y	0044325	molecular_function	transmembrane transporter binding
Y	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
Y	0046872	molecular_function	metal ion binding
Y	0048306	molecular_function	calcium-dependent protein binding
Y	0050998	molecular_function	nitric-oxide synthase binding
Y	0051592	biological_process	response to calcium ion
Y	0055117	biological_process	regulation of cardiac muscle contraction
Y	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
Y	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
Y	0071346	biological_process	cellular response to type II interferon
Y	0072542	molecular_function	protein phosphatase activator activity
Y	0090150	biological_process	establishment of protein localization to membrane
Y	0090151	biological_process	establishment of protein localization to mitochondrial membrane
Y	0097225	cellular_component	sperm midpiece
Y	0098901	biological_process	regulation of cardiac muscle cell action potential
Y	0140056	biological_process	organelle localization by membrane tethering
Y	1900242	biological_process	regulation of synaptic vesicle endocytosis
Y	1902494	cellular_component	catalytic complex
Y	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
Y	2000300	biological_process	regulation of synaptic vesicle exocytosis

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
D	ASP20-LEU32
D	ASP56-PHE68
D	ASP93-LEU105
D	ASP129-PHE141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:23109337, ECO:0000269|PubMed:3145979, ECO:0007744|PDB:1G4Y, ECO:0007744|PDB:1NIW, ECO:0007744|PDB:2HQW, ECO:0007744|PDB:2YGG, ECO:0007744|PDB:3B32, ECO:0007744|PDB:3BXK, ECO:0007744|PDB:3BXL, ECO:0007744|PDB:3CLN, ECO:0007744|PDB:3IFK, ECO:0007744|PDB:3SJQ, ECO:0007744|PDB:4EHQ, ECO:0007744|PDB:4G27, ECO:0007744|PDB:4G28, ECO:0007744|PDB:4I2Y, ECO:0007744|PDB:4J9Y, ECO:0007744|PDB:4J9Z, ECO:0007744|PDB:4QNH

Chain	Residue	Details
D	LYS21
I	LEU32
B	LYS21
B	GLY23
B	GLY25
B	ILE27
B	LEU32
J	LYS21
J	GLY23
J	GLY25
J	ILE27
D	GLY23
J	LEU32
K	LYS21
K	GLY23
K	GLY25
K	ILE27
K	LEU32
T	LYS21
T	GLY23
T	GLY25
T	ILE27
D	GLY25
T	LEU32
R	LYS21
R	GLY23
R	GLY25
R	ILE27
R	LEU32
Y	LYS21
Y	GLY23
Y	GLY25
Y	ILE27
D	ILE27
Y	LEU32
D	LEU32
I	LYS21
I	GLY23
I	GLY25
I	ILE27

---

site_id	SWS_FT_FI2
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:23109337, ECO:0000269|PubMed:3145979, ECO:0007744|PDB:1G4Y, ECO:0007744|PDB:1NIW, ECO:0007744|PDB:2HQW, ECO:0007744|PDB:2YGG, ECO:0007744|PDB:3B32, ECO:0007744|PDB:3BXK, ECO:0007744|PDB:3BXL, ECO:0007744|PDB:3CLN, ECO:0007744|PDB:3EK4, ECO:0007744|PDB:3EK7, ECO:0007744|PDB:3EK8, ECO:0007744|PDB:3EKH, ECO:0007744|PDB:3EVR, ECO:0007744|PDB:3EVU, ECO:0007744|PDB:3IFK, ECO:0007744|PDB:3SG2, ECO:0007744|PDB:3SG3, ECO:0007744|PDB:3SG4, ECO:0007744|PDB:3SG5, ECO:0007744|PDB:3SG6, ECO:0007744|PDB:3SG7, ECO:0007744|PDB:3SJQ, ECO:0007744|PDB:3WLC, ECO:0007744|PDB:3WLD, ECO:0007744|PDB:4EHQ, ECO:0007744|PDB:4G27, ECO:0007744|PDB:4G28, ECO:0007744|PDB:4I2Y, ECO:0007744|PDB:4J9Y, ECO:0007744|PDB:4J9Z, ECO:0007744|PDB:4QNH

Chain	Residue	Details
D	ALA57
I	PHE68
B	ALA57
B	GLY59
B	GLY61
B	ILE63
B	PHE68
J	ALA57
J	GLY59
J	GLY61
J	ILE63
D	GLY59
J	PHE68
K	ALA57
K	GLY59
K	GLY61
K	ILE63
K	PHE68
T	ALA57
T	GLY59
T	GLY61
T	ILE63
D	GLY61
T	PHE68
R	ALA57
R	GLY59
R	GLY61
R	ILE63
R	PHE68
Y	ALA57
Y	GLY59
Y	GLY61
Y	ILE63
D	ILE63
Y	PHE68
D	PHE68
I	ALA57
I	GLY59
I	GLY61
I	ILE63

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:23109337, ECO:0000269|PubMed:3145979, ECO:0007744|PDB:1NIW, ECO:0007744|PDB:2HQW, ECO:0007744|PDB:2YGG, ECO:0007744|PDB:3BXK, ECO:0007744|PDB:3BXL, ECO:0007744|PDB:3CLN, ECO:0007744|PDB:3EK4, ECO:0007744|PDB:3EK7, ECO:0007744|PDB:3EK8, ECO:0007744|PDB:3EKH, ECO:0007744|PDB:3EVR, ECO:0007744|PDB:3EVU, ECO:0007744|PDB:3SG2, ECO:0007744|PDB:3SG3, ECO:0007744|PDB:3SG4, ECO:0007744|PDB:3SG5, ECO:0007744|PDB:3SG6, ECO:0007744|PDB:3SG7, ECO:0007744|PDB:3SJQ, ECO:0007744|PDB:3WLC, ECO:0007744|PDB:3WLD, ECO:0007744|PDB:4EHQ, ECO:0007744|PDB:4I2Y, ECO:0007744|PDB:4RJD

Chain	Residue	Details
D	LYS94
I	LEU105
B	LYS94
B	GLY96
B	GLY98
B	ILE100
B	LEU105
J	LYS94
J	GLY96
J	GLY98
J	ILE100
D	GLY96
J	LEU105
K	LYS94
K	GLY96
K	GLY98
K	ILE100
K	LEU105
T	LYS94
T	GLY96
T	GLY98
T	ILE100
D	GLY98
T	LEU105
R	LYS94
R	GLY96
R	GLY98
R	ILE100
R	LEU105
Y	LYS94
Y	GLY96
Y	GLY98
Y	ILE100
D	ILE100
Y	LEU105
D	LEU105
I	LYS94
I	GLY96
I	GLY98
I	ILE100

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:23109337, ECO:0000269|PubMed:3145979, ECO:0007744|PDB:1NIW, ECO:0007744|PDB:2HQW, ECO:0007744|PDB:2YGG, ECO:0007744|PDB:3BXK, ECO:0007744|PDB:3BXL, ECO:0007744|PDB:3CLN, ECO:0007744|PDB:3EK7, ECO:0007744|PDB:3EK8, ECO:0007744|PDB:3EKH, ECO:0007744|PDB:3EVR, ECO:0007744|PDB:3EVU, ECO:0007744|PDB:3SG2, ECO:0007744|PDB:3SG3, ECO:0007744|PDB:3SG4, ECO:0007744|PDB:3SG5, ECO:0007744|PDB:3SG7, ECO:0007744|PDB:3SJQ, ECO:0007744|PDB:3WLC, ECO:0007744|PDB:3WLD, ECO:0007744|PDB:4EHQ, ECO:0007744|PDB:4I2Y, ECO:0007744|PDB:4RJD

Chain	Residue	Details
D	ILE130
I	PHE141
B	ILE130
B	GLY132
B	GLY134
B	VAL136
B	PHE141
J	ILE130
J	GLY132
J	GLY134
J	VAL136
D	GLY132
J	PHE141
K	ILE130
K	GLY132
K	GLY134
K	VAL136
K	PHE141
T	ILE130
T	GLY132
T	GLY134
T	VAL136
D	GLY134
T	PHE141
R	ILE130
R	GLY132
R	GLY134
R	VAL136
R	PHE141
Y	ILE130
Y	GLY132
Y	GLY134
Y	VAL136
D	VAL136
Y	PHE141
D	PHE141
I	ILE130
I	GLY132
I	GLY134
I	VAL136

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:201628, ECO:0000269|Ref.8

Chain	Residue	Details
D	ASP2
I	ASP2
B	ASP2
J	ASP2
K	ASP2
T	ASP2
R	ASP2
Y	ASP2

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	ASP22
I	ASP22
B	ASP22
J	ASP22
K	ASP22
T	ASP22
R	ASP22
Y	ASP22

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	MOD_RES: Phosphothreonine; by CaMK4 => ECO:0000269|PubMed:12392717

Chain	Residue	Details
D	GLU45
I	GLU45
B	GLU45
J	GLU45
K	GLU45
T	GLU45
R	GLU45
Y	GLU45

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	GLU82
I	GLU82
B	GLU82
J	GLU82
K	GLU82
T	GLU82
R	GLU82
Y	GLU82

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	ASP95
I	ASP95
B	ASP95
J	ASP95
K	ASP95
T	ASP95
R	ASP95
Y	ASP95

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:22673903

Chain	Residue	Details
D	ILE100
I	ILE100
B	ILE100
J	ILE100
K	ILE100
T	ILE100
R	ILE100
Y	ILE100

---

site_id	SWS_FT_FI11
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903

Chain	Residue	Details
D	ALA102
I	ALA102
B	ALA102
J	ALA102
K	ALA102
T	ALA102
R	ALA102
Y	ALA102

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	ASN111
I	ASN111
B	ASN111
J	ASN111
K	ASN111
T	ASN111
R	ASN111
Y	ASN111

---

site_id	SWS_FT_FI13
Number of Residues	8
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	LEU116
I	LEU116
B	LEU116
J	LEU116
K	LEU116
T	LEU116
R	LEU116
Y	LEU116

---

site_id	SWS_FT_FI14
Number of Residues	8
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
D	GLU139
I	GLU139
B	GLU139
J	GLU139
K	GLU139
T	GLU139
R	GLU139
Y	GLU139

---

site_id	SWS_FT_FI15
Number of Residues	16
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157

Chain	Residue	Details
D	ASP22
T	ASP22
R	ASP22
Y	ASP22
I	ASP22
B	ASP22
J	ASP22
K	ASP22

---