1QW9
Crystal structure of a family 51 alpha-L-arabinofuranosidase in complex with 4-nitrophenyl-Ara
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0031222 | biological_process | arabinan catabolic process |
| A | 0046373 | biological_process | L-arabinose metabolic process |
| A | 0046556 | molecular_function | alpha-L-arabinofuranosidase activity |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0031222 | biological_process | arabinan catabolic process |
| B | 0046373 | biological_process | L-arabinose metabolic process |
| B | 0046556 | molecular_function | alpha-L-arabinofuranosidase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:11943144, ECO:0000305|PubMed:12221104, ECO:0000305|PubMed:14517232 |
| Chain | Residue | Details |
| A | MET176 | |
| B | MET176 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:12221104, ECO:0000305|PubMed:14517232 |
| Chain | Residue | Details |
| A | TRP295 | |
| B | TRP295 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14517232, ECO:0007744|PDB:1PZ2, ECO:0007744|PDB:1QW8, ECO:0007744|PDB:1QW9 |
| Chain | Residue | Details |
| A | HIS30 | |
| A | PHE75 | |
| A | TYR247 | |
| B | HIS30 | |
| B | PHE75 | |
| B | TYR247 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14517232, ECO:0007744|PDB:1PZ2, ECO:0007744|PDB:1QW9 |
| Chain | Residue | Details |
| A | ALA175 | |
| B | ALA175 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: covalent => ECO:0000269|PubMed:14517232, ECO:0007744|PDB:1PZ2, ECO:0007744|PDB:1QW8, ECO:0007744|PDB:1QW9 |
| Chain | Residue | Details |
| A | TRP295 | |
| B | TRP295 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14517232, ECO:0007744|PDB:1QW8, ECO:0007744|PDB:1QW9 |
| Chain | Residue | Details |
| A | LEU352 | |
| B | LEU352 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Important for substrate recognition => ECO:0000305|PubMed:14517232 |
| Chain | Residue | Details |
| A | TYR299 | |
| A | LEU352 | |
| B | TYR299 | |
| B | LEU352 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1pz3 |
| Chain | Residue | Details |
| A | ALA175 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1pz3 |
| Chain | Residue | Details |
| B | ALA175 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 667 |
| Chain | Residue | Details |
| A | MET176 | activator, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| A | TRP295 | covalently attached, nucleofuge, nucleophile |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 667 |
| Chain | Residue | Details |
| B | MET176 | activator, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| B | TRP295 | covalently attached, nucleofuge, nucleophile |
