1QVY
Crystal structure of RhoGDI K(199,200)R double mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007266 | biological_process | Rho protein signal transduction |
| B | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0007266 | biological_process | Rho protein signal transduction |
| C | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0007266 | biological_process | Rho protein signal transduction |
| D | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0007266 | biological_process | Rho protein signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ARG199 |
| A | ARG200 |
| A | HOH1096 |
| A | HOH1140 |
| A | HOH1142 |
| A | HOH1148 |
| A | HOH1172 |
| B | ARG199 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| B | ARG172 |
| B | ARG199 |
| B | ARG200 |
| B | HOH1113 |
| B | HOH1158 |
| B | HOH1223 |
| A | ARG199 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1003 |
| Chain | Residue |
| C | ARG199 |
| C | ARG200 |
| C | HOH1063 |
| C | HOH1074 |
| C | HOH1080 |
| D | ARG199 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1004 |
| Chain | Residue |
| C | ARG199 |
| D | ARG172 |
| D | ARG199 |
| D | ARG200 |
| D | HOH1067 |
| D | HOH1115 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
| Chain | Residue |
| A | VAL78 |
| A | ARG111 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1006 |
| Chain | Residue |
| A | PRO68 |
| A | ASN69 |
| A | ARG120 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1007 |
| Chain | Residue |
| B | HIS131 |
| B | ARG180 |
| B | HOH1145 |
| B | HOH1181 |
| B | HOH1210 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1008 |
| Chain | Residue |
| D | HIS131 |
| D | ARG180 |
| D | HOH1056 |
| D | HOH1076 |
| D | HOH1200 |
| D | HOH1201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS105 | |
| D | LYS105 | |
| D | LYS127 | |
| D | LYS178 | |
| A | LYS127 | |
| A | LYS178 | |
| B | LYS105 | |
| B | LYS127 | |
| B | LYS178 | |
| C | LYS105 | |
| C | LYS127 | |
| C | LYS178 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99PT1 |
| Chain | Residue | Details |
| A | LYS141 | |
| B | LYS141 | |
| C | LYS141 | |
| D | LYS141 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| A | LYS138 | |
| D | LYS138 | |
| D | LYS141 | |
| A | LYS141 | |
| B | LYS138 | |
| B | LYS141 | |
| C | LYS138 | |
| C | LYS141 |
