1QRQ

STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005249	molecular_function	voltage-gated potassium channel activity
A	0005737	cellular_component	cytoplasm
A	0006813	biological_process	potassium ion transport
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport
B	0005249	molecular_function	voltage-gated potassium channel activity
B	0005737	cellular_component	cytoplasm
B	0006813	biological_process	potassium ion transport
B	0016020	cellular_component	membrane
B	0055085	biological_process	transmembrane transport
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0005737	cellular_component	cytoplasm
C	0006813	biological_process	potassium ion transport
C	0016020	cellular_component	membrane
C	0055085	biological_process	transmembrane transport
D	0005249	molecular_function	voltage-gated potassium channel activity
D	0005737	cellular_component	cytoplasm
D	0006813	biological_process	potassium ion transport
D	0016020	cellular_component	membrane
D	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NDP A 1000

Chain	Residue
A	GLY55
A	ARG189
A	GLN214
A	TRP243
A	SER244
A	PRO245
A	LEU246
A	ALA247
A	CYS248
A	GLY249
A	SER252
A	THR56
A	LYS254
A	ILE259
A	TYR262
A	SER263
A	ARG264
A	LEU321
A	GLY323
A	SER325
A	GLN329
A	GLU332
A	TRP57
A	ASN333
A	HOH1026
A	HOH1029
A	HOH1031
A	GLN63
A	ASP85
A	TYR90
A	LYS118
A	ASN158
A	SER188

---

site_id	AC2
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NDP B 1001

Chain	Residue
B	GLY55
B	THR56
B	TRP57
B	GLN63
B	ASP85
B	TYR90
B	LYS118
B	ASN158
B	SER188
B	ARG189
B	GLN214
B	TRP243
B	SER244
B	PRO245
B	LEU246
B	ALA247
B	CYS248
B	GLY249
B	SER252
B	LYS254
B	ILE259
B	TYR262
B	SER263
B	ARG264
B	LEU321
B	GLY323
B	SER325
B	GLN329
B	GLU332
B	ASN333
B	HOH1027
B	HOH1030
B	HOH1032

---

site_id	AC3
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NDP C 1002

Chain	Residue
C	GLY55
C	THR56
C	TRP57
C	GLN63
C	ASP85
C	TYR90
C	LYS118
C	ASN158
C	SER188
C	ARG189
C	GLN214
C	TRP243
C	SER244
C	PRO245
C	LEU246
C	ALA247
C	CYS248
C	GLY249
C	SER252
C	LYS254
C	ILE259
C	TYR262
C	SER263
C	ARG264
C	LEU321
C	GLY323
C	SER325
C	GLN329
C	GLU332
C	ASN333
C	HOH1031
C	HOH1034
C	HOH1036

---

site_id	AC4
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NDP D 1003

Chain	Residue
D	GLY55
D	THR56
D	TRP57
D	GLN63
D	ASP85
D	TYR90
D	LYS118
D	ASN158
D	SER188
D	ARG189
D	GLN214
D	TRP243
D	SER244
D	PRO245
D	LEU246
D	ALA247
D	CYS248
D	GLY249
D	SER252
D	LYS254
D	ILE259
D	TYR262
D	SER263
D	ARG264
D	LEU321
D	GLY323
D	SER325
D	GLN329
D	GLU332
D	ASN333
D	HOH1032
D	HOH1035
D	HOH1037

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:18672894

Chain	Residue	Details
A	TYR90
B	TYR90
C	TYR90
D	TYR90

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	THR56
A	LYS254
A	ARG264
A	SER325
A	GLN329
A	ASN333
B	THR56
B	TRP57
B	GLN63
B	ASP85
B	SER188
A	TRP57
B	GLN214
B	TRP243
B	SER244
B	LEU246
B	LYS254
B	ARG264
B	SER325
B	GLN329
B	ASN333
C	THR56
A	GLN63
C	TRP57
C	GLN63
C	ASP85
C	SER188
C	GLN214
C	TRP243
C	SER244
C	LEU246
C	LYS254
C	ARG264
A	ASP85
C	SER325
C	GLN329
C	ASN333
D	THR56
D	TRP57
D	GLN63
D	ASP85
D	SER188
D	GLN214
D	TRP243
A	SER188
D	SER244
D	LEU246
D	LYS254
D	ARG264
D	SER325
D	GLN329
D	ASN333
A	GLN214
A	TRP243
A	SER244
A	LEU246

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:4JTA

Chain	Residue	Details
A	ASN158
B	ASN158
C	ASN158
D	ASN158

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	ARG189
B	ARG189
C	ARG189
D	ARG189

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	PRO245
B	PRO245
C	PRO245
D	PRO245

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:4JTA

Chain	Residue	Details
A	ALA247
B	ALA247
C	ALA247
D	ALA247

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	CYS248
B	CYS248
C	CYS248
D	CYS248

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	TYR262
B	TYR262
C	TYR262
D	TYR262

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:23705070, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	GLY323
B	GLY323
C	GLY323
D	GLY323

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD

Chain	Residue	Details
A	GLU332
B	GLU332
C	GLU332
D	GLU332

---

site_id	SWS_FT_FI11
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:21357749

Chain	Residue	Details
A	SER112
B	SER112
C	SER112
D	SER112

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q13303

Chain	Residue	Details
A	LYS124
B	LYS124
C	LYS124
D	LYS124

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 2alr

Chain	Residue	Details
A	TYR90
A	LYS118

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 2alr

Chain	Residue	Details
B	TYR90
B	LYS118

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 2alr

Chain	Residue	Details
C	TYR90
C	LYS118

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 2alr

Chain	Residue	Details
D	TYR90
D	LYS118

---