1QRQ
STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005249 | molecular_function | voltage-gated potassium channel activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006813 | biological_process | potassium ion transport |
A | 0016020 | cellular_component | membrane |
A | 0055085 | biological_process | transmembrane transport |
B | 0005249 | molecular_function | voltage-gated potassium channel activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006813 | biological_process | potassium ion transport |
B | 0016020 | cellular_component | membrane |
B | 0055085 | biological_process | transmembrane transport |
C | 0005249 | molecular_function | voltage-gated potassium channel activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006813 | biological_process | potassium ion transport |
C | 0016020 | cellular_component | membrane |
C | 0055085 | biological_process | transmembrane transport |
D | 0005249 | molecular_function | voltage-gated potassium channel activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006813 | biological_process | potassium ion transport |
D | 0016020 | cellular_component | membrane |
D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NDP A 1000 |
Chain | Residue |
A | GLY55 |
A | ARG189 |
A | GLN214 |
A | TRP243 |
A | SER244 |
A | PRO245 |
A | LEU246 |
A | ALA247 |
A | CYS248 |
A | GLY249 |
A | SER252 |
A | THR56 |
A | LYS254 |
A | ILE259 |
A | TYR262 |
A | SER263 |
A | ARG264 |
A | LEU321 |
A | GLY323 |
A | SER325 |
A | GLN329 |
A | GLU332 |
A | TRP57 |
A | ASN333 |
A | HOH1026 |
A | HOH1029 |
A | HOH1031 |
A | GLN63 |
A | ASP85 |
A | TYR90 |
A | LYS118 |
A | ASN158 |
A | SER188 |
site_id | AC2 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NDP B 1001 |
Chain | Residue |
B | GLY55 |
B | THR56 |
B | TRP57 |
B | GLN63 |
B | ASP85 |
B | TYR90 |
B | LYS118 |
B | ASN158 |
B | SER188 |
B | ARG189 |
B | GLN214 |
B | TRP243 |
B | SER244 |
B | PRO245 |
B | LEU246 |
B | ALA247 |
B | CYS248 |
B | GLY249 |
B | SER252 |
B | LYS254 |
B | ILE259 |
B | TYR262 |
B | SER263 |
B | ARG264 |
B | LEU321 |
B | GLY323 |
B | SER325 |
B | GLN329 |
B | GLU332 |
B | ASN333 |
B | HOH1027 |
B | HOH1030 |
B | HOH1032 |
site_id | AC3 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NDP C 1002 |
Chain | Residue |
C | GLY55 |
C | THR56 |
C | TRP57 |
C | GLN63 |
C | ASP85 |
C | TYR90 |
C | LYS118 |
C | ASN158 |
C | SER188 |
C | ARG189 |
C | GLN214 |
C | TRP243 |
C | SER244 |
C | PRO245 |
C | LEU246 |
C | ALA247 |
C | CYS248 |
C | GLY249 |
C | SER252 |
C | LYS254 |
C | ILE259 |
C | TYR262 |
C | SER263 |
C | ARG264 |
C | LEU321 |
C | GLY323 |
C | SER325 |
C | GLN329 |
C | GLU332 |
C | ASN333 |
C | HOH1031 |
C | HOH1034 |
C | HOH1036 |
site_id | AC4 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NDP D 1003 |
Chain | Residue |
D | GLY55 |
D | THR56 |
D | TRP57 |
D | GLN63 |
D | ASP85 |
D | TYR90 |
D | LYS118 |
D | ASN158 |
D | SER188 |
D | ARG189 |
D | GLN214 |
D | TRP243 |
D | SER244 |
D | PRO245 |
D | LEU246 |
D | ALA247 |
D | CYS248 |
D | GLY249 |
D | SER252 |
D | LYS254 |
D | ILE259 |
D | TYR262 |
D | SER263 |
D | ARG264 |
D | LEU321 |
D | GLY323 |
D | SER325 |
D | GLN329 |
D | GLU332 |
D | ASN333 |
D | HOH1032 |
D | HOH1035 |
D | HOH1037 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:18672894 |
Chain | Residue | Details |
A | TYR90 | |
B | TYR90 | |
C | TYR90 | |
D | TYR90 |
site_id | SWS_FT_FI2 |
Number of Residues | 56 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | THR56 | |
A | LYS254 | |
A | ARG264 | |
A | SER325 | |
A | GLN329 | |
A | ASN333 | |
B | THR56 | |
B | TRP57 | |
B | GLN63 | |
B | ASP85 | |
B | SER188 | |
A | TRP57 | |
B | GLN214 | |
B | TRP243 | |
B | SER244 | |
B | LEU246 | |
B | LYS254 | |
B | ARG264 | |
B | SER325 | |
B | GLN329 | |
B | ASN333 | |
C | THR56 | |
A | GLN63 | |
C | TRP57 | |
C | GLN63 | |
C | ASP85 | |
C | SER188 | |
C | GLN214 | |
C | TRP243 | |
C | SER244 | |
C | LEU246 | |
C | LYS254 | |
C | ARG264 | |
A | ASP85 | |
C | SER325 | |
C | GLN329 | |
C | ASN333 | |
D | THR56 | |
D | TRP57 | |
D | GLN63 | |
D | ASP85 | |
D | SER188 | |
D | GLN214 | |
D | TRP243 | |
A | SER188 | |
D | SER244 | |
D | LEU246 | |
D | LYS254 | |
D | ARG264 | |
D | SER325 | |
D | GLN329 | |
D | ASN333 | |
A | GLN214 | |
A | TRP243 | |
A | SER244 | |
A | LEU246 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:4JTA |
Chain | Residue | Details |
A | ASN158 | |
B | ASN158 | |
C | ASN158 | |
D | ASN158 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | ARG189 | |
B | ARG189 | |
C | ARG189 | |
D | ARG189 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | PRO245 | |
B | PRO245 | |
C | PRO245 | |
D | PRO245 |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:4JTA |
Chain | Residue | Details |
A | ALA247 | |
B | ALA247 | |
C | ALA247 | |
D | ALA247 |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:18806782, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3EAU, ECO:0007744|PDB:3EB3, ECO:0007744|PDB:3EB4, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | CYS248 | |
B | CYS248 | |
C | CYS248 | |
D | CYS248 |
site_id | SWS_FT_FI8 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | TYR262 | |
B | TYR262 | |
C | TYR262 | |
D | TYR262 |
site_id | SWS_FT_FI9 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:23705070, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | GLY323 | |
B | GLY323 | |
C | GLY323 | |
D | GLY323 |
site_id | SWS_FT_FI10 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:10399921, ECO:0000269|PubMed:10884227, ECO:0000269|PubMed:16002581, ECO:0000269|PubMed:18004376, ECO:0000269|PubMed:20360102, ECO:0000269|PubMed:20534430, ECO:0000269|PubMed:23705070, ECO:0007744|PDB:1EXB, ECO:0007744|PDB:1QRQ, ECO:0007744|PDB:2A79, ECO:0007744|PDB:2R9R, ECO:0007744|PDB:3LNM, ECO:0007744|PDB:3LUT, ECO:0007744|PDB:4JTA, ECO:0007744|PDB:4JTC, ECO:0007744|PDB:4JTD |
Chain | Residue | Details |
A | GLU332 | |
B | GLU332 | |
C | GLU332 | |
D | GLU332 |
site_id | SWS_FT_FI11 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:21357749 |
Chain | Residue | Details |
A | SER112 | |
B | SER112 | |
C | SER112 | |
D | SER112 |
site_id | SWS_FT_FI12 |
Number of Residues | 4 |
Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q13303 |
Chain | Residue | Details |
A | LYS124 | |
B | LYS124 | |
C | LYS124 | |
D | LYS124 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 2alr |
Chain | Residue | Details |
A | TYR90 | |
A | LYS118 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 2alr |
Chain | Residue | Details |
B | TYR90 | |
B | LYS118 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 2alr |
Chain | Residue | Details |
C | TYR90 | |
C | LYS118 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 2alr |
Chain | Residue | Details |
D | TYR90 | |
D | LYS118 |