1QPG

3-PHOSPHOGLYCERATE KINASE, MUTATION R65Q

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004618	molecular_function	phosphoglycerate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0016301	molecular_function	kinase activity
A	0043531	molecular_function	ADP binding
A	0047134	molecular_function	protein-disulfide reductase (NAD(P)H) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE MAP A 450

Chain	Residue
A	GLY211
A	VAL339
A	PHE340
A	GLU341
A	GLY370
A	GLY371
A	ASP372
A	THR373
A	HOH541
A	HOH545
A	GLY235
A	GLY236
A	PHE239
A	GLY310
A	ASN334
A	GLY335
A	PRO336
A	GLY338

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 3PG A 451

Chain	Residue
A	ASP23
A	ASN25
A	ARG38
A	HIS62
A	ARG121
A	GLY164
A	HOH537

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Functional Information from PROSITE/UniProt

site_id	PS00111
Number of Residues	11
Details	PGLYCERATE_KINASE Phosphoglycerate kinase signature. RVFIRvDfNVP

Chain	Residue	Details
A	ARG17-PRO27

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING:

Chain	Residue	Details
A	PHE24
A	LEU63
A	ILE218
A	LEU311
A	GLY335
A	PHE342
A	GLY371

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:6765200, ECO:0000269|PubMed:8672447

Chain	Residue	Details
A	ILE39
A	TYR122
A	ALA169

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	LEU2

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site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
A	PHE93
A	ARG203
A	PHE241

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site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	ALA110
A	SER172
A	ARG318

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358

Chain	Residue	Details
A	ARG130

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site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950

Chain	Residue	Details
A	LEU154

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	VAL298

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site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	ILE331

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site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	GLY392

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site_id	SWS_FT_FI11
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047

Chain	Residue	Details
A	GLU82
A	ALA197
A	ALA258
A	GLY274
A	GLU302

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 13pk

Chain	Residue	Details
A	ARG38
A	LYS213
A	GLY371
A	GLY394

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