Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0015232 | molecular_function | heme transmembrane transporter activity |
| A | 0015886 | biological_process | heme transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0015232 | molecular_function | heme transmembrane transporter activity |
| B | 0015886 | biological_process | heme transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 501 |
| Chain | Residue |
| A | ALA284 |
| A | PHE285 |
| A | ALA336 |
| A | PHE337 |
| A | VAL338 |
| A | ALA379 |
| A | LEU380 |
| A | CYS381 |
| A | NA522 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 511 |
| Chain | Residue |
| A | THR36 |
| A | ALA77 |
| A | ALA123 |
| A | SER167 |
| A | ALA168 |
| A | NA513 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 512 |
| Chain | Residue |
| A | ASP34 |
| A | ASP75 |
| A | ASP121 |
| A | THR166 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 513 |
| Chain | Residue |
| A | THR36 |
| A | ALA77 |
| A | ALA123 |
| A | ALA168 |
| A | CL511 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 521 |
| Chain | Residue |
| A | ALA284 |
| A | ALA335 |
| A | ALA336 |
| A | ALA379 |
| A | NA522 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 522 |
| Chain | Residue |
| A | MET239 |
| A | ALA284 |
| A | ALA336 |
| A | ALA379 |
| A | PO4501 |
| A | CL521 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 523 |
| Chain | Residue |
| A | SER237 |
| A | ASP282 |
| A | ASP334 |
| A | ASP377 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 501 |
| Chain | Residue |
| B | ALA284 |
| B | PHE285 |
| B | ALA336 |
| B | PHE337 |
| B | VAL338 |
| B | ALA379 |
| B | LEU380 |
| B | CYS381 |
| B | NA522 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 511 |
| Chain | Residue |
| B | ALA35 |
| B | THR36 |
| B | ALA77 |
| B | SER167 |
| B | ALA168 |
| B | NA513 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 512 |
| Chain | Residue |
| B | ASP34 |
| B | ASP75 |
| B | ASP121 |
| B | THR166 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 513 |
| Chain | Residue |
| B | THR36 |
| B | ALA77 |
| B | ALA123 |
| B | ALA168 |
| B | CL511 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 521 |
| Chain | Residue |
| B | ALA284 |
| B | ALA335 |
| B | ALA336 |
| B | ALA379 |
| B | NA522 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 522 |
| Chain | Residue |
| B | MET239 |
| B | ALA284 |
| B | ALA336 |
| B | ALA379 |
| B | PO4501 |
| B | CL521 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 523 |
| Chain | Residue |
| B | SER237 |
| B | ASP282 |
| B | ASP334 |
| B | ASP377 |
| site_id | BC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | HIS56 |
| A | TRP171 |
| A | ARG174 |
| A | TYR176 |
| A | ARG185 |
| A | TYR197 |
| A | PHE205 |
| A | HIS213 |
| A | HIS225 |
| A | SER227 |
| A | HIS266 |
| A | PRO269 |
| A | HIS272 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | ARG214 |
| B | HIS266 |
| B | HIS56 |
| B | TYR176 |
| B | PHE183 |
| B | TYR197 |
| B | LEU199 |
| B | TYR204 |
| B | PHE205 |
| B | HIS213 |
Functional Information from PROSITE/UniProt
| site_id | PS00024 |
| Number of Residues | 16 |
| Details | HEMOPEXIN Hemopexin domain signature. IAhqWpqgPsTVDAAF |
| Chain | Residue | Details |
| A | ILE270-PHE285 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS56 | |
| A | HIS127 | |
| A | HIS213 | |
| A | HIS266 | |
| B | HIS56 | |
| B | HIS127 | |
| B | HIS213 | |
| B | HIS266 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | ASN9 | |
| B | ASN9 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN41 | |
| A | ASN164 | |
| A | ASN219 | |
| B | ASN41 | |
| B | ASN164 | |
| B | ASN219 | |
