Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0003824 | molecular_function | catalytic activity |
A | 0004802 | molecular_function | transketolase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006098 | biological_process | pentose-phosphate shunt |
A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
A | 0016740 | molecular_function | transferase activity |
A | 0016744 | molecular_function | transketolase or transaldolase activity |
A | 0030145 | molecular_function | manganese ion binding |
A | 0030976 | molecular_function | thiamine pyrophosphate binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0004802 | molecular_function | transketolase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006098 | biological_process | pentose-phosphate shunt |
B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
B | 0016740 | molecular_function | transferase activity |
B | 0016744 | molecular_function | transketolase or transaldolase activity |
B | 0030145 | molecular_function | manganese ion binding |
B | 0030976 | molecular_function | thiamine pyrophosphate binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA A 675 |
Chain | Residue |
A | ASP155 |
A | ASN185 |
A | ILE187 |
A | TPP670 |
A | HOH706 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 680 |
Chain | Residue |
B | ARG358 |
B | SER385 |
B | HIS461 |
B | ARG520 |
B | HOH954 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 675 |
Chain | Residue |
B | ASP155 |
B | ASN185 |
B | ILE187 |
B | TPP670 |
B | HOH712 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 680 |
Chain | Residue |
A | ARG358 |
A | SER385 |
A | HIS461 |
A | ARG520 |
A | HOH1174 |
A | HOH1215 |
site_id | AC5 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE TPP A 670 |
Chain | Residue |
A | ALA29 |
A | HIS66 |
A | GLY114 |
A | LEU116 |
A | ASP155 |
A | GLY156 |
A | GLU160 |
A | ASN185 |
A | ILE187 |
A | ILE189 |
A | ILE247 |
A | HIS261 |
A | CA675 |
A | HOH706 |
A | HOH754 |
A | HOH767 |
B | ASP381 |
B | GLU411 |
B | PHE437 |
B | TYR440 |
B | HOH1103 |
site_id | AC6 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE TPP B 670 |
Chain | Residue |
A | ASP381 |
A | GLU411 |
A | PHE437 |
A | TYR440 |
A | HOH1085 |
B | ALA29 |
B | HIS66 |
B | GLY114 |
B | LEU116 |
B | ASP155 |
B | GLY156 |
B | GLU160 |
B | ASN185 |
B | ILE187 |
B | ILE189 |
B | ILE247 |
B | HIS261 |
B | CA675 |
B | HOH712 |
B | HOH800 |
B | HOH876 |
site_id | TPA |
Number of Residues | 14 |
Details | COFACTOR BINDING |
Chain | Residue |
A | HIS66 |
A | HIS261 |
B | ASP381 |
B | GLU411 |
B | PHE437 |
B | TYR440 |
A | GLY114 |
A | LEU116 |
A | ASP155 |
A | GLY156 |
A | ASN185 |
A | ILE187 |
A | SER188 |
A | ILE189 |
site_id | TPB |
Number of Residues | 14 |
Details | COFACTOR BINDING |
Chain | Residue |
B | HIS66 |
B | GLY114 |
B | LEU116 |
B | ASP155 |
B | GLY156 |
B | ASN185 |
B | ILE187 |
B | SER188 |
B | ILE189 |
B | HIS261 |
A | ASP381 |
A | GLU411 |
A | PHE437 |
A | TYR440 |
Functional Information from PROSITE/UniProt
site_id | PS00801 |
Number of Residues | 21 |
Details | TRANSKETOLASE_1 Transketolase signature 1. RalsMDavqkakSGHPGapMG |
Chain | Residue | Details |
A | ARG12-GLY32 | |
site_id | PS00802 |
Number of Residues | 17 |
Details | TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPVEqvAslR |
Chain | Residue | Details |
A | GLY467-ARG483 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000305 |
Chain | Residue | Details |
A | GLU411 | |
B | GLU411 | |
Chain | Residue | Details |
A | HIS26 | |
B | SER385 | |
B | HIS461 | |
B | ASP469 | |
B | HIS473 | |
B | ARG520 | |
A | ARG358 | |
A | SER385 | |
A | HIS461 | |
A | ASP469 | |
A | HIS473 | |
A | ARG520 | |
B | HIS26 | |
B | ARG358 | |
Chain | Residue | Details |
A | HIS66 | |
A | GLY114 | |
A | ASN185 | |
A | HIS261 | |
B | HIS66 | |
B | GLY114 | |
B | ASN185 | |
B | HIS261 | |
Chain | Residue | Details |
A | ASP155 | |
A | ILE187 | |
B | ASP155 | |
B | ILE187 | |
Chain | Residue | Details |
A | GLY156 | |
B | GLY156 | |
Chain | Residue | Details |
A | PHE437 | |
B | PHE437 | |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | SITE: Important for catalytic activity |
Chain | Residue | Details |
A | HIS26 | |
A | HIS261 | |
B | HIS26 | |
B | HIS261 | |
Chain | Residue | Details |
A | LYS46 | |
B | LYS46 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | SER251 | |
site_id | CSA10 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | HIS258 | |
site_id | CSA11 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS261 | |
A | HIS26 | |
site_id | CSA12 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | HIS261 | |
B | HIS26 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | SER251 | |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | GLU411 | |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | GLU411 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS473 | |
A | GLU411 | |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | HIS473 | |
B | GLU411 | |
site_id | CSA7 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | PRO252 | |
site_id | CSA8 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | PRO252 | |
site_id | CSA9 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS258 | |