Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0044164 | cellular_component | host cell cytosol |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090729 | molecular_function | toxin activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0044164 | cellular_component | host cell cytosol |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 9001 |
| Chain | Residue |
| A | HIS686 |
| A | HIS690 |
| A | TYR728 |
| A | GLU735 |
| A | NSC9002 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 9002 |
| Chain | Residue |
| B | NSC9003 |
| B | HIS686 |
| B | HIS690 |
| B | TYR728 |
| B | GLU735 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NSC A 9002 |
| Chain | Residue |
| A | ASP328 |
| A | PHE329 |
| A | SER655 |
| A | TYR659 |
| A | GLU687 |
| A | HIS690 |
| A | TYR728 |
| A | GLU735 |
| A | ZN9001 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NSC B 9003 |
| Chain | Residue |
| B | SER655 |
| B | LYS656 |
| B | GLY657 |
| B | LEU658 |
| B | TYR659 |
| B | VAL675 |
| B | GLU687 |
| B | HIS690 |
| B | TYR728 |
| B | GLU735 |
| B | ZN9002 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. GFIHEFGHAV |
| Chain | Residue | Details |
| A | GLY683-VAL692 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU687 | |
| B | GLU687 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01339, ECO:0000269|PubMed:11700563, ECO:0000269|PubMed:14718924, ECO:0000269|PubMed:14718925, ECO:0000269|PubMed:15911756, ECO:0000269|PubMed:22342144, ECO:0000269|PubMed:25372673, ECO:0000269|PubMed:26492514, ECO:0000269|PubMed:26578066, ECO:0007744|PDB:1J7N, ECO:0007744|PDB:1PWP, ECO:0007744|PDB:1PWQ, ECO:0007744|PDB:1PWU, ECO:0007744|PDB:1PWW, ECO:0007744|PDB:1YQY, ECO:0007744|PDB:4DV8, ECO:0007744|PDB:4PKQ, ECO:0007744|PDB:4PKR, ECO:0007744|PDB:4PKS, ECO:0007744|PDB:4PKT, ECO:0007744|PDB:4PKV, ECO:0007744|PDB:4PKW, ECO:0007744|PDB:4WF6, ECO:0007744|PDB:4XM6, ECO:0007744|PDB:4XM7, ECO:0007744|PDB:5D1S, ECO:0007744|PDB:5D1T |
| Chain | Residue | Details |
| A | HIS686 | |
| A | HIS690 | |
| A | GLU735 | |
| B | HIS686 | |
| B | HIS690 | |
| B | GLU735 | |
| Chain | Residue | Details |
| A | TYR728 | |
| B | TYR728 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 641 |
| Chain | Residue | Details |
| A | HIS686 | metal ligand |
| A | GLU687 | proton acceptor, proton donor |
| A | HIS690 | metal ligand |
| A | TYR728 | electrostatic stabiliser |
| A | GLU735 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 641 |
| Chain | Residue | Details |
| B | HIS686 | metal ligand |
| B | GLU687 | proton acceptor, proton donor |
| B | HIS690 | metal ligand |
| B | TYR728 | electrostatic stabiliser |
| B | GLU735 | metal ligand |
