1PRE
PROAEROLYSIN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001897 | biological_process | symbiont-mediated cytolysis of host cell |
| A | 0005576 | cellular_component | extracellular region |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0090729 | molecular_function | toxin activity |
| B | 0001897 | biological_process | symbiont-mediated cytolysis of host cell |
| B | 0005576 | cellular_component | extracellular region |
| B | 0020002 | cellular_component | host cell plasma membrane |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Region: {"description":"Interaction with host N-linked glycan"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 64 |
| Details | Region: {"description":"Part of the transmembrane beta-barrel after proteolytic activation of the toxin and insertion into the host membrane"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Region: {"description":"Interaction with glycans from host GPI-anchor"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for oligomerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for heptamerization"} |
| Chain | Residue | Details |
