Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0047866 | molecular_function | dimethylglycine oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 2001 |
| Chain | Residue |
| A | ASP257 |
| A | VAL412 |
| A | HOH2944 |
| A | HOH3153 |
| A | HOH3552 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FOL A 2887 |
| Chain | Residue |
| A | PHE632 |
| A | LEU649 |
| A | TYR651 |
| A | GLU658 |
| A | TYR699 |
| A | HOH2971 |
| A | HOH2987 |
| A | HOH3177 |
| A | HOH3240 |
| A | HOH3265 |
| A | HOH3374 |
| A | HOH3674 |
| A | HOH3701 |
| A | HOH3929 |
| A | LEU508 |
| A | TYR539 |
| A | THR554 |
| A | TYR631 |
| site_id | AC3 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 902 |
| Chain | Residue |
| A | GLY11 |
| A | GLY13 |
| A | ILE14 |
| A | VAL15 |
| A | ASP35 |
| A | GLN36 |
| A | PRO42 |
| A | GLY44 |
| A | SER45 |
| A | THR46 |
| A | HIS48 |
| A | ALA49 |
| A | PRO50 |
| A | GLY51 |
| A | LEU52 |
| A | THR172 |
| A | VAL174 |
| A | CYS202 |
| A | ALA203 |
| A | GLY204 |
| A | TRP206 |
| A | ILE210 |
| A | HIS225 |
| A | TYR259 |
| A | GLY333 |
| A | ILE334 |
| A | VAL360 |
| A | TRP361 |
| A | VAL362 |
| A | THR363 |
| A | HOH2909 |
| A | HOH2911 |
| A | HOH2912 |
| A | HOH2915 |
| A | HOH2945 |
| A | HOH2992 |
| A | HOH3010 |
| A | HOH3143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For 5,10-methylenetetrahydrofolate synthesis activity","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12912903","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19369258","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19369258","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"12912903","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"19369258","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12912903","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Pros-8alpha-FAD histidine"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pj5 |
| Chain | Residue | Details |
| A | TYR259 | |
| A | ASP552 | |
| A | HIS225 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 879 |
| Chain | Residue | Details |
| A | HIS225 | proton shuttle (general acid/base) |
| A | TYR259 | proton shuttle (general acid/base) |
| A | ASP552 | proton shuttle (general acid/base) |
