1PFO

PERFRINGOLYSIN O

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015485	molecular_function	cholesterol binding

Functional Information from PDB Data

site_id	ACT
Number of Residues	1
Details	ACTIVE SITE CYSTEINE OF THE TRP-RICH MOTIF.

Chain	Residue
A	CYS459

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Functional Information from PROSITE/UniProt

site_id	PS00481
Number of Residues	12
Details	THIOL_CYTOLYSINS Thiol-activated cytolysins signature. RECTGLaWEWWR

Chain	Residue	Details
A	ARG457-ARG468

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	TRANSMEM: Beta stranded => ECO:0000250|UniProtKB:Q04IN8

Chain	Residue	Details
A	LYS189-VAL202
A	VAL209-GLU218
A	SER287-ALA296
A	LYS304-SER316

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Important for cholesterol binding => ECO:0000305|PubMed:2888650

Chain	Residue	Details
A	CYS459

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