Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE E6C A 213 |
Chain | Residue |
A | GLN19 |
A | ASP158 |
A | MOH216 |
A | HOH232 |
A | HOH404 |
A | GLY23 |
A | SER24 |
A | CYS25 |
A | TYR61 |
A | ASN64 |
A | GLY65 |
A | GLY66 |
A | VAL157 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MOH A 214 |
Chain | Residue |
A | ARG41 |
A | THR42 |
A | HOH283 |
site_id | AC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MOH A 215 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MOH A 216 |
Chain | Residue |
A | VAL110 |
A | ARG111 |
A | E6C213 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MOH A 218 |
Chain | Residue |
A | GLY20 |
A | HOH231 |
A | HOH232 |
site_id | AC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MOH A 219 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MOH A 220 |
Chain | Residue |
A | ARG41 |
A | LYS211 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MOH A 221 |
Chain | Residue |
A | ILE148 |
A | ASN169 |
A | LYS190 |
site_id | AC9 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MOH A 222 |
site_id | BC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MOH A 223 |
Chain | Residue |
A | TYR78 |
A | HOH259 |
site_id | BC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MOH A 224 |
Chain | Residue |
A | ASN127 |
A | HOH230 |
A | HOH292 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MOH A 225 |
Chain | Residue |
A | LYS100 |
A | TRP177 |
A | THR179 |
A | GLY180 |
site_id | BC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MOH A 226 |
Functional Information from PROSITE/UniProt
site_id | PS00139 |
Number of Residues | 12 |
Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGSCWAfSA |
Chain | Residue | Details |
A | GLN19-ALA30 | |
site_id | PS00639 |
Number of Residues | 11 |
Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VDHAVAAVGYG |
Chain | Residue | Details |
A | VAL157-GLY167 | |
site_id | PS00640 |
Number of Residues | 20 |
Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YILiKNSWgtgWGenGYIrI |
Chain | Residue | Details |
A | TYR170-ILE189 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS25 | |
Chain | Residue | Details |
A | HIS159 | |
Chain | Residue | Details |
A | ASN175 | |
Chain | Residue | Details |
A | CYS25 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | ASN175 | |
A | CYS25 | |
A | HIS159 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | GLN19 | |
A | CYS25 | |
A | HIS159 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | ASN175 | |
A | GLN19 | |
A | HIS159 | |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 174 |
Chain | Residue | Details |
A | GLN19 | electrostatic stabiliser, hydrogen bond donor |
A | CYS25 | electrostatic stabiliser |
A | HIS159 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | ASN175 | activator, electrostatic stabiliser, hydrogen bond acceptor |