1PDQ
Polycomb chromodomain complexed with the histone H3 tail containing trimethyllysine 27.
Functional Information from PROSITE/UniProt
| site_id | PS00598 |
| Number of Residues | 21 |
| Details | CHROMO_1 Chromo domain signature. YrVKWkGWnqryn.TWEPevnI |
| Chain | Residue | Details |
| A | TYR43-ILE63 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| B | ALA15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| B | ALA24 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708, ECO:0000269|PubMed:7309716 |
| Chain | Residue | Details |
| B | SER28 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Interaction with ZMYND11 => ECO:0000269|PubMed:24590075 |
| Chain | Residue | Details |
| B | THR32 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:15345777, ECO:0000269|PubMed:16497732, ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| B | LYS18 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| B | GLN19 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| B | M3L27 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:15851689, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| B | ALA29 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:15851689, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| B | THR32 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | LIPID: N6-decanoyllysine => ECO:0000269|PubMed:35939806 |
| Chain | Residue | Details |
| B | GLN19 |
