1P4K
CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003948 | molecular_function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0042597 | cellular_component | periplasmic space |
| C | 0003948 | molecular_function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| C | 0042597 | cellular_component | periplasmic space |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 296 |
| Chain | Residue |
| A | HIS150 |
| A | GLY204 |
| A | GOL297 |
| A | THR152 |
| A | THR170 |
| A | GLY172 |
| A | MET173 |
| A | ARG180 |
| A | GLY182 |
| A | ASP183 |
| A | SER184 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL A 297 |
| Chain | Residue |
| A | HIS150 |
| A | THR152 |
| A | THR170 |
| A | GLY172 |
| A | MET173 |
| A | ARG180 |
| A | GLY182 |
| A | ASP183 |
| A | SER184 |
| A | GLY204 |
| A | GLY206 |
| A | GOL296 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL C 2 |
| Chain | Residue |
| C | GOL4 |
| C | HIS450 |
| C | THR452 |
| C | THR470 |
| C | GLY472 |
| C | MET473 |
| C | ARG480 |
| C | GLY482 |
| C | ASP483 |
| C | SER484 |
| C | GLY504 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL C 4 |
| Chain | Residue |
| C | GOL2 |
| C | HIS450 |
| C | THR470 |
| C | GLY472 |
| C | MET473 |
| C | ARG480 |
| C | GLY482 |
| C | ASP483 |
| C | SER484 |
| C | GLY504 |
| C | GLY506 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"10490104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17157318","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20800597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9685368","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1apy |
| Chain | Residue | Details |
| A | GLY204 | |
| A | THR152 | |
| A | THR170 | |
| A | SER50 | |
| A | THR203 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1apy |
| Chain | Residue | Details |
| C | SER350 | |
| C | THR452 | |
| C | GLY504 | |
| C | THR503 | |
| C | THR470 |
