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1P15

Crystal structure of the D2 domain of RPTPa

Functional Information from GO Data
ChainGOidnamespacecontents
A0004725molecular_functionprotein tyrosine phosphatase activity
A0006470biological_processprotein dephosphorylation
A0016311biological_processdephosphorylation
B0004725molecular_functionprotein tyrosine phosphatase activity
B0006470biological_processprotein dephosphorylation
B0016311biological_processdephosphorylation
Functional Information from PROSITE/UniProt
site_idPS00383
Number of Residues11
DetailsTYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGagRTG
ChainResidueDetails
AVAL722-GLY732

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Phosphocysteine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1bzc
ChainResidueDetails
AARG730
AGLU691
ACYS724
ATHR731

site_idCSA2
Number of Residues4
DetailsAnnotated By Reference To The Literature 1bzc
ChainResidueDetails
BARG730
BGLU691
BCYS724
BTHR731

243083

PDB entries from 2025-10-15

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