1OYY
Structure of the RecQ Catalytic Core bound to ATP-gamma-S
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003678 | molecular_function | DNA helicase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0009432 | biological_process | SOS response |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 524 |
| Chain | Residue |
| A | CYS380 |
| A | CYS397 |
| A | GLY398 |
| A | CYS400 |
| A | CYS403 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN A 525 |
| Chain | Residue |
| A | GLU10 |
| A | GLU31 |
| A | ASP35 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 526 |
| Chain | Residue |
| A | HOH528 |
| A | HOH529 |
| A | HOH568 |
| A | AGS527 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE AGS A 527 |
| Chain | Residue |
| A | TYR23 |
| A | GLN25 |
| A | ARG27 |
| A | GLN30 |
| A | THR49 |
| A | GLY50 |
| A | GLY51 |
| A | GLY52 |
| A | LYS53 |
| A | SER54 |
| A | LEU55 |
| A | ALA182 |
| A | ARG329 |
| A | MN526 |
| A | HOH528 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 168 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1OYW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14517231","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1OYY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1OYY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14517231","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
