1OQB
The Crystal Structure of the one-iron form of the di-iron center in Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean).
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0009507 | cellular_component | chloroplast |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0009507 | cellular_component | chloroplast |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0009507 | cellular_component | chloroplast |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006631 | biological_process | fatty acid metabolic process |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0009507 | cellular_component | chloroplast |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0006631 | biological_process | fatty acid metabolic process |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0009507 | cellular_component | chloroplast |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0006631 | biological_process | fatty acid metabolic process |
| F | 0006633 | biological_process | fatty acid biosynthetic process |
| F | 0009507 | cellular_component | chloroplast |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0045300 | molecular_function | stearoyl-[ACP] desaturase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0102786 | molecular_function | obsolete stearoyl-[acp] desaturase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 A 364 |
| Chain | Residue |
| A | GLU105 |
| A | GLU143 |
| A | HIS146 |
| A | GLU229 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 B 364 |
| Chain | Residue |
| B | GLU105 |
| B | GLU143 |
| B | HIS146 |
| B | GLU229 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 C 364 |
| Chain | Residue |
| C | GLU143 |
| C | HIS146 |
| C | GLU229 |
| C | GLU105 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 D 364 |
| Chain | Residue |
| D | GLU105 |
| D | GLU143 |
| D | HIS146 |
| D | GLU229 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 E 364 |
| Chain | Residue |
| E | GLU105 |
| E | GLU143 |
| E | HIS146 |
| E | GLU229 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE2 F 364 |
| Chain | Residue |
| F | GLU105 |
| F | GLU143 |
| F | HIS146 |
| F | GLU229 |
Functional Information from PROSITE/UniProt
| site_id | PS00574 |
| Number of Residues | 20 |
| Details | FATTY_ACID_DESATUR_2 Fatty acid desaturases family 2 signature. SAvaqRLgvytakDYadILE |
| Chain | Residue | Details |
| A | SER283-GLU302 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12704186, ECO:0000269|PubMed:17088542, ECO:0000269|PubMed:8861937 |
| Chain | Residue | Details |
| A | GLU105 | |
| B | GLU196 | |
| B | GLU229 | |
| B | HIS232 | |
| C | GLU105 | |
| C | GLU143 | |
| C | HIS146 | |
| C | GLU196 | |
| C | GLU229 | |
| C | HIS232 | |
| D | GLU105 | |
| A | GLU143 | |
| D | GLU143 | |
| D | HIS146 | |
| D | GLU196 | |
| D | GLU229 | |
| D | HIS232 | |
| E | GLU105 | |
| E | GLU143 | |
| E | HIS146 | |
| E | GLU196 | |
| E | GLU229 | |
| A | HIS146 | |
| E | HIS232 | |
| F | GLU105 | |
| F | GLU143 | |
| F | HIS146 | |
| F | GLU196 | |
| F | GLU229 | |
| F | HIS232 | |
| A | GLU196 | |
| A | GLU229 | |
| A | HIS232 | |
| B | GLU105 | |
| B | GLU143 | |
| B | HIS146 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| A | THR199 | |
| A | ASP228 | |
| A | TRP62 | |
| A | HIS146 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| B | THR199 | |
| B | ASP228 | |
| B | TRP62 | |
| B | HIS146 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| C | THR199 | |
| C | ASP228 | |
| C | TRP62 | |
| C | HIS146 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| D | THR199 | |
| D | ASP228 | |
| D | TRP62 | |
| D | HIS146 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| E | THR199 | |
| E | ASP228 | |
| E | TRP62 | |
| E | HIS146 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1afr |
| Chain | Residue | Details |
| F | THR199 | |
| F | ASP228 | |
| F | TRP62 | |
| F | HIS146 |
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| A | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| A | GLU105 | metal ligand |
| A | GLU143 | metal ligand |
| A | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| A | GLU196 | metal ligand |
| A | THR199 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| A | GLU229 | metal ligand |
| A | HIS232 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| B | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| B | GLU105 | metal ligand |
| B | GLU143 | metal ligand |
| B | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| B | GLU196 | metal ligand |
| B | THR199 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| B | GLU229 | metal ligand |
| B | HIS232 | metal ligand |
| site_id | MCSA3 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| C | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| C | GLU105 | metal ligand |
| C | GLU143 | metal ligand |
| C | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| C | GLU196 | metal ligand |
| C | THR199 | electrostatic stabiliser, hydrogen bond donor |
| C | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| C | GLU229 | metal ligand |
| C | HIS232 | metal ligand |
| site_id | MCSA4 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| D | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| D | GLU105 | metal ligand |
| D | GLU143 | metal ligand |
| D | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| D | GLU196 | metal ligand |
| D | THR199 | electrostatic stabiliser, hydrogen bond donor |
| D | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| D | GLU229 | metal ligand |
| D | HIS232 | metal ligand |
| site_id | MCSA5 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| E | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| E | GLU105 | metal ligand |
| E | GLU143 | metal ligand |
| E | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| E | GLU196 | metal ligand |
| E | THR199 | electrostatic stabiliser, hydrogen bond donor |
| E | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| E | GLU229 | metal ligand |
| E | HIS232 | metal ligand |
| site_id | MCSA6 |
| Number of Residues | 9 |
| Details | M-CSA 136 |
| Chain | Residue | Details |
| F | TRP62 | hydrogen bond donor, single electron acceptor, single electron donor, single electron relay |
| F | GLU105 | metal ligand |
| F | GLU143 | metal ligand |
| F | HIS146 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| F | GLU196 | metal ligand |
| F | THR199 | electrostatic stabiliser, hydrogen bond donor |
| F | ASP228 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| F | GLU229 | metal ligand |
| F | HIS232 | metal ligand |
