1OO0

Crystal structure of the Drosophila Mago nashi-Y14 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A	0000226	biological_process	microtubule cytoskeleton organization
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005681	cellular_component	spliceosomal complex
A	0005737	cellular_component	cytoplasm
A	0007315	biological_process	germ plasm assembly
A	0007317	biological_process	regulation of germ plasm oskar mRNA localization
A	0008103	biological_process	oocyte microtubule cytoskeleton polarization
A	0008104	biological_process	intracellular protein localization
A	0008380	biological_process	RNA splicing
A	0010628	biological_process	positive regulation of gene expression
A	0016325	biological_process	oocyte microtubule cytoskeleton organization
A	0035145	cellular_component	exon-exon junction complex
A	0042564	cellular_component	NLS-dependent protein nuclear import complex
A	0045451	biological_process	germ plasm oskar mRNA localization
A	0046594	biological_process	maintenance of germ plasm mRNA location
A	0048477	biological_process	oogenesis
A	0051170	biological_process	import into nucleus
A	0060293	cellular_component	germ plasm
A	0071011	cellular_component	precatalytic spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071030	biological_process	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing
A	1990501	cellular_component	exon-exon junction subcomplex mago-y14
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006396	biological_process	RNA processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SR A 401

Chain	Residue
A	ASN38
A	ASN40
A	ASN43
A	THR45
A	HOH603
A	HOH626
A	HOH690

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BME A 301

Chain	Residue
A	PHE135
A	HOH629
A	GLN128
A	CYS132

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BME A 302

Chain	Residue
A	ARG28

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site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD A 501

Chain	Residue
A	GLY106
A	SER107
A	LEU108
A	VAL111
A	TYR124
A	TYR125
A	HOH660
B	ASN135

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD A 502

Chain	Residue
A	GLY13
A	HIS14
A	LYS15
A	ASP82
A	ARG86

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 601

Chain	Residue
B	ASN135
B	GLN145
B	ASP147
B	HOH624

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 602

Chain	Residue
A	GLU24
A	GLU26
A	ARG34
A	ALA36
A	HOH632
A	HOH678

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	78
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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