1OMD
STRUCTURE OF ONCOMODULIN REFINED AT 1.85 ANGSTROMS RESOLUTION. AN EXAMPLE OF EXTENSIVE MOLECULAR AGGREGATION VIA CA2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009611 | biological_process | response to wounding |
| A | 0031982 | cellular_component | vesicle |
| A | 0032420 | cellular_component | stereocilium |
| A | 0032437 | cellular_component | cuticular plate |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0044877 | molecular_function | protein-containing complex binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090102 | biological_process | cochlea development |
| A | 0099512 | cellular_component | supramolecular fiber |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 109 |
| Chain | Residue |
| A | ASP90 |
| A | ASP92 |
| A | ASP94 |
| A | LYS96 |
| A | GLU101 |
| A | HOH111 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 110 |
| Chain | Residue |
| A | ASP51 |
| A | ASP53 |
| A | SER55 |
| A | TYR57 |
| A | GLU62 |
| A | HOH112 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 135 |
| Chain | Residue |
| A | GLN54 |
| A | GLN71 |
| A | ASP73 |
| A | GLU79 |
| A | HOH169 |
| A | HOH172 |
| site_id | CD |
| Number of Residues | 12 |
| Details | CALCIUM BINDING SITE 1 |
| Chain | Residue |
| A | ASP51 |
| A | GLY60 |
| A | ASP61 |
| A | GLU62 |
| A | ASN52 |
| A | ASP53 |
| A | GLN54 |
| A | SER55 |
| A | GLY56 |
| A | TYR57 |
| A | LEU58 |
| A | ASP59 |
| site_id | EF |
| Number of Residues | 12 |
| Details | CALCIUM BINDING SITE 2 |
| Chain | Residue |
| A | ASP90 |
| A | ASN91 |
| A | ASP92 |
| A | GLY93 |
| A | ASP94 |
| A | GLY95 |
| A | LYS96 |
| A | ILE97 |
| A | GLY98 |
| A | ALA99 |
| A | ASP100 |
| A | GLU101 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DNDQSGYLDgdEL |
| Chain | Residue | Details |
| A | ASP51-LEU63 | |
| A | ASP90-PHE102 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 31 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"2231727","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8487302","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
