1OLM

Supernatant Protein Factor in Complex with RRR-alpha-Tocopherylquinone: A Link between Oxidized Vitamin E and Cholesterol Biosynthesis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005543	molecular_function	phospholipid binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0008431	molecular_function	vitamin E binding
A	0045540	biological_process	regulation of cholesterol biosynthetic process
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0070062	cellular_component	extracellular exosome
C	0005543	molecular_function	phospholipid binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008289	molecular_function	lipid binding
C	0008431	molecular_function	vitamin E binding
C	0045540	biological_process	regulation of cholesterol biosynthetic process
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0070062	cellular_component	extracellular exosome
E	0005543	molecular_function	phospholipid binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0008289	molecular_function	lipid binding
E	0008431	molecular_function	vitamin E binding
E	0045540	biological_process	regulation of cholesterol biosynthetic process
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE VTQ A1322

Chain	Residue
A	LEU106
A	ILE205
A	HOH2298
A	HOH2299
A	LYS124
A	TYR153
A	HIS162
A	ALA167
A	TYR171
A	LEU175
A	LEU186
A	LEU189

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE VTQ C1323

Chain	Residue
C	ILE103
C	LEU106
C	LYS124
C	TYR153
C	HIS162
C	ALA167
C	TYR171
C	PHE178
C	PHE198
C	HOH2295

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE VTQ E1398

Chain	Residue
E	LEU106
E	TYR153
E	HIS162
E	ALA167
E	TYR171
E	PHE178
E	LEU189
E	HOH2280
E	HOH2281

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08

Chain	Residue	Details
E	LYS51
E	LYS253
E	LYS257
E	LYS393
C	LYS51
C	LYS253
C	LYS257
C	LYS393

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