Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005576 | cellular_component | extracellular region |
B | 0005615 | cellular_component | extracellular space |
B | 0006508 | biological_process | proteolysis |
B | 0008236 | molecular_function | serine-type peptidase activity |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR CHAIN C OF SCYPTOLIN A |
Chain | Residue |
A | THR44 |
A | SER203 |
A | THR221 |
A | SER222 |
A | PHE223 |
A | VAL224 |
A | SER225 |
A | ARG226 |
A | HOH2014 |
B | LEU149 |
B | ASN153 |
A | CYS45 |
B | GLY154 |
B | GLN200 |
C | HOH2001 |
C | HOH2002 |
D | CNT1262 |
A | HIS60 |
A | VAL103 |
A | GLY198 |
A | CYS199 |
A | GLN200 |
A | GLY201 |
A | ASP202 |
site_id | AC2 |
Number of Residues | 23 |
Details | BINDING SITE FOR CHAIN D OF SCYPTOLIN A |
Chain | Residue |
A | ASN153 |
A | GLN200 |
A | ARG226 |
B | THR44 |
B | CYS45 |
B | HIS60 |
B | VAL103 |
B | GLY198 |
B | CYS199 |
B | GLN200 |
B | GLY201 |
B | ASP202 |
B | SER203 |
B | THR221 |
B | SER222 |
B | PHE223 |
B | VAL224 |
B | SER225 |
B | ARG226 |
C | THR1258 |
C | CNT1262 |
D | HOH2001 |
D | HOH2002 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MTAAHC |
Chain | Residue | Details |
A | MET56-CYS61 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SGcqGDSGGPLH |
Chain | Residue | Details |
A | SER197-HIS208 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS60 | |
B | HIS60 | |
Chain | Residue | Details |
A | ASP108 | |
A | SER203 | |
B | ASP108 | |
B | SER203 | |
Chain | Residue | Details |
A | GLU74 | |
A | ASN76 | |
A | GLN79 | |
A | GLU84 | |
B | GLU74 | |
B | ASN76 | |
B | GLN79 | |
B | GLU84 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | HIS60 | |
A | SER203 | |
A | ASP108 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | HIS60 | |
B | SER203 | |
B | ASP108 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | GLY201 | |
A | HIS60 | |
A | SER203 | |
A | ASP108 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | GLY201 | |
B | HIS60 | |
B | SER203 | |
B | ASP108 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | GLY204 | |
A | HIS60 | |
A | SER203 | |
A | ASP108 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | GLY204 | |
B | HIS60 | |
B | SER203 | |
B | ASP108 | |
site_id | CSA7 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | GLY201 | |
A | HIS60 | |
A | SER222 | |
A | SER203 | |
A | ASP108 | |
site_id | CSA8 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | GLY201 | |
B | HIS60 | |
B | SER222 | |
B | SER203 | |
B | ASP108 | |