1OJR

L-rhamnulose-1-phosphate aldolase from Escherichia coli (mutant E192A)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005996	biological_process	monosaccharide metabolic process
A	0008994	molecular_function	rhamnulose-1-phosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0016832	molecular_function	aldehyde-lyase activity
A	0019301	biological_process	rhamnose catabolic process
A	0019318	biological_process	hexose metabolic process
A	0019323	biological_process	pentose catabolic process
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A1275

Chain	Residue
A	HIS141
A	HIS143
A	HIS212
A	2HA1277
A	PO41278
A	HOH2503

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PO4 A1276

Chain	Residue
A	GLY76
A	THR115
A	SER116
A	PO41278
A	HOH2497
A	HOH2498
A	HOH2499
A	HOH2500
A	HOH2501
A	HOH2502
A	ASN29
A	ASN32
A	SER75

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PO4 A1278

Chain	Residue
A	GLY31
A	ASN32
A	GLU117
A	HIS141
A	HIS143
A	HIS212
A	ZN1275
A	PO41276
A	GOL1279
A	HOH2497
A	HOH2502
A	HOH2503

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 2HA A1277

Chain	Residue
A	ASN29
A	GLY30
A	GLY31
A	ASN32
A	GLU117
A	HIS141
A	HIS143
A	HIS212
A	ZN1275
A	GOL1279
A	HOH2502
A	HOH2507

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DIO A1283

Chain	Residue
A	HIS46
A	ASP47
A	PHE49
A	GLN51
A	TYR55
A	HOH2524
A	HOH2525

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A1279

Chain	Residue
A	ASN29
A	GLU171
A	PRO188
A	PHE263
A	2HA1277
A	PO41278
A	HOH2115
A	HOH2503
A	HOH2504
A	HOH2505
A	HOH2507

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A1280

Chain	Residue
A	GLY76
A	LYS77
A	ASN81
A	ASP222
A	GLU223
A	HOH2508

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A1281

Chain	Residue
A	ARG80
A	GLN83
A	HOH2075
A	HOH2510
A	HOH2511
A	HOH2514
A	HOH2517
A	HOH2518
A	HOH2519

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A1282

Chain	Residue
A	LEU154
A	TYR242
A	MET244
A	LYS248
A	HOH2520
A	HOH2521
A	HOH2522

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"11976494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12962479","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11976494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12962479","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1gt7

Chain	Residue	Details
A	GLU117
A	GLU171

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1gt7

Chain	Residue	Details
A	VAL174

---

site_id	MCSA1
Number of Residues	5
Details	M-CSA 645

Chain	Residue	Details
A	GLU117	proton acceptor, proton donor
A	HIS141	metal ligand
A	HIS143	metal ligand
A	GLU171	proton donor
A	HIS212	metal ligand

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