Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE HEM A 1407 |
Chain | Residue |
A | MET87 |
A | ARG295 |
A | TYR319 |
A | ALA346 |
A | PHE347 |
A | HIS352 |
A | CYS354 |
A | GLY356 |
A | PIM1408 |
A | HOH2409 |
A | HOH2454 |
A | HIS95 |
A | ARG99 |
A | PHE106 |
A | MET239 |
A | ALA242 |
A | THR246 |
A | THR247 |
A | LEU283 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PIM A 1408 |
Chain | Residue |
A | TRP81 |
A | PHE88 |
A | LEU238 |
A | SER241 |
A | ALA242 |
A | THR246 |
A | HEM1407 |
A | HOH2314 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGVHFCLG |
Chain | Residue | Details |
A | PHE347-GLY356 | |