1ODJ

PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005829	cellular_component	cytosol
A	0006152	biological_process	purine nucleoside catabolic process
A	0006218	biological_process	uridine catabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005829	cellular_component	cytosol
B	0006152	biological_process	purine nucleoside catabolic process
B	0006218	biological_process	uridine catabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005829	cellular_component	cytosol
C	0006152	biological_process	purine nucleoside catabolic process
C	0006218	biological_process	uridine catabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
D	0003824	molecular_function	catalytic activity
D	0004731	molecular_function	purine-nucleoside phosphorylase activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005829	cellular_component	cytosol
D	0006152	biological_process	purine nucleoside catabolic process
D	0006218	biological_process	uridine catabolic process
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
E	0003824	molecular_function	catalytic activity
E	0004731	molecular_function	purine-nucleoside phosphorylase activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005829	cellular_component	cytosol
E	0006152	biological_process	purine nucleoside catabolic process
E	0006218	biological_process	uridine catabolic process
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
F	0003824	molecular_function	catalytic activity
F	0004731	molecular_function	purine-nucleoside phosphorylase activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005829	cellular_component	cytosol
F	0006152	biological_process	purine nucleoside catabolic process
F	0006218	biological_process	uridine catabolic process
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A1236

Chain	Residue
A	GLY21
A	ARG25
A	ARG87
A	GLY89
A	THR90
A	GMP1237
B	ARG44

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B1236

Chain	Residue
B	ARG25
B	ARG87
B	VAL88
B	GLY89
B	THR90
B	GMP1237
A	ARG44
B	GLY21

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 C1236

Chain	Residue
C	GLY21
C	ARG25
C	ARG87
C	VAL88
C	GLY89
C	THR90
C	GMP1237
D	ARG44

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D1236

Chain	Residue
C	ARG44
D	GLY21
D	ARG25
D	ARG87
D	GLY89
D	THR90
D	GMP1237

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E1236

Chain	Residue
E	GLY21
E	ARG25
E	ARG87
E	GLY89
E	THR90
E	GMP1237
F	ARG44

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 F1236

Chain	Residue
E	ARG44
F	GLY21
F	ARG25
F	ARG87
F	GLY89
F	THR90
F	GMP1237

---

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GMP A1237

Chain	Residue
A	MET65
A	ARG87
A	THR90
A	ALA91
A	GLY92
A	GLU156
A	PHE159
A	PHE178
A	GLU179
A	MET180
A	GLU181
A	SER203
A	ILE206
A	SO41236
A	HOH2047
B	HIS5
B	ARG44

---

site_id	AC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GMP B1237

Chain	Residue
A	HIS5
A	ARG44
B	MET65
B	ARG87
B	THR90
B	ALA91
B	GLY92
B	GLU156
B	PHE159
B	GLU179
B	MET180
B	GLU181
B	ASN204
B	ILE206
B	SO41236
B	HOH2050

---

site_id	AC9
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GMP C1237

Chain	Residue
C	ARG87
C	THR90
C	ALA91
C	GLY92
C	GLU156
C	PHE159
C	PHE178
C	GLU179
C	MET180
C	GLU181
C	SO41236
D	HIS5
D	ARG44

---

site_id	BC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GMP D1237

Chain	Residue
D	GLU181
D	SER203
D	ASN204
D	SO41236
D	HOH2023
C	HIS5
D	ARG87
D	THR90
D	ALA91
D	GLY92
D	GLU156
D	PHE159
D	PHE178
D	MET180

---

site_id	BC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GMP E1237

Chain	Residue
E	ARG87
E	THR90
E	ALA91
E	GLY92
E	GLU156
E	PHE159
E	PHE178
E	GLU179
E	MET180
E	GLU181
E	SER203
E	SO41236
E	HOH2040
F	HIS5
F	ARG44

---

site_id	BC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GMP F1237

Chain	Residue
E	HIS5
E	ARG44
F	MET65
F	ARG87
F	THR90
F	ALA91
F	GLY92
F	GLU156
F	PHE159
F	PHE178
F	GLU179
F	MET180
F	GLU181
F	SER203
F	ASN204
F	ILE206
F	SO41236
F	HOH2060

---

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. TtGMGtPSaAIvveEL

Chain	Residue	Details
A	THR62-LEU77

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