Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 308 |
| Chain | Residue |
| A | ARG122 |
| A | SER128 |
| A | ARG242 |
| A | HOH2150 |
| A | HOH2269 |
| A | HOH2270 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 310 |
| Chain | Residue |
| A | TYR292 |
| A | ASP239 |
| A | ASP259 |
| A | LYS260 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 311 |
| Chain | Residue |
| A | GLY18 |
| A | LYS19 |
| A | VAL20 |
| A | ARG21 |
| A | AMP307 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AMP A 307 |
| Chain | Residue |
| A | ARG21 |
| A | ILE23 |
| A | PHE33 |
| A | HIS75 |
| A | HIS110 |
| A | LYS111 |
| A | HIS112 |
| A | LEU114 |
| A | LYS164 |
| A | GLU219 |
| A | VAL232 |
| A | ASP233 |
| A | SO4311 |
| A | HOH2264 |
| A | HOH2266 |
| A | HOH2267 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE AMP A 309 |
| Chain | Residue |
| A | GLU62 |
| A | LEU76 |
| A | VAL77 |
| A | ILE79 |
| A | ILE85 |
| A | SER106 |
| A | LEU107 |
| A | LEU108 |
| A | GLU253 |
| A | HOH2271 |
| A | HOH2272 |
| A | HOH2273 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. LIPLEvIVRgyiTGS |
| Chain | Residue | Details |
| A | LEU114-SER128 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. IADtKFEFG |
| Chain | Residue | Details |
| A | ILE213-GLY221 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"9551557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
