1OAB
CRYSTAL STRUCTURE OF THE TYROSINE REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH PHOSPHOENOLPYRUVATE AND MANGANESE(II)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 400 |
| Chain | Residue |
| A | CYS76 |
| A | HIS282 |
| A | GLU316 |
| A | ASP342 |
| A | PEP508 |
| A | HOH2207 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 400 |
| Chain | Residue |
| B | ASP342 |
| B | PEP508 |
| B | HOH2206 |
| B | CYS76 |
| B | HIS282 |
| B | GLU316 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PEP A 508 |
| Chain | Residue |
| A | ARG107 |
| A | TYR109 |
| A | LYS112 |
| A | GLY178 |
| A | ALA179 |
| A | ARG180 |
| A | LYS201 |
| A | ARG249 |
| A | HIS282 |
| A | MN400 |
| A | HOH2052 |
| A | HOH2093 |
| A | HOH2207 |
| A | HOH2208 |
| A | HOH2209 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP B 508 |
| Chain | Residue |
| B | ARG107 |
| B | TYR109 |
| B | LYS112 |
| B | GLY178 |
| B | ALA179 |
| B | ARG180 |
| B | LYS201 |
| B | ARG249 |
| B | HIS282 |
| B | MN400 |
| B | HOH2053 |
| B | HOH2206 |
| B | HOH2207 |
| B | HOH2208 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| A | HIS282 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| B | HIS282 |
