Functional Information from GO Data
| Chain | GOid | namespace | contents |
| H | 0004252 | molecular_function | serine-type endopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
| L | 0005509 | molecular_function | calcium ion binding |
| L | 0005576 | cellular_component | extracellular region |
| T | 0007596 | biological_process | blood coagulation |
| T | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CR9 H 258 |
| Chain | Residue |
| H | CYS42 |
| H | GLY219 |
| H | CYS220 |
| H | GLY226 |
| H | HOH271 |
| H | HOH289 |
| H | HIS57 |
| H | ASP189 |
| H | SER190 |
| H | LYS192 |
| H | SER195 |
| H | VAL213 |
| H | SER214 |
| H | TRP215 |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDqlqsYiCfC |
| Chain | Residue | Details |
| L | CYS61-CYS72 | |
| site_id | PS00011 |
| Number of Residues | 26 |
| Details | GLA_1 Vitamin K-dependent carboxylation domain. EckEEqCsfeearEifkdaertkl.FW |
| Chain | Residue | Details |
| L | GLU16-TRP41 | |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CfClpAfeGRnC |
| Chain | Residue | Details |
| L | CYS70-CYS81 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| H | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| H | ASP189-ALA200 | |
| site_id | PS00621 |
| Number of Residues | 18 |
| Details | TISSUE_FACTOR Tissue factor signature. WKsKCfyTtDTECDLTDE |
| Chain | Residue | Details |
| T | TRP45-GLU62 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| L | CYS112-CYS127 | |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DgDQCassp..........Cqnggs..CkDqlqsYiC |
| Chain | Residue | Details |
| L | ASP46-CYS70 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| T | ASN124 | |
| T | ASN137 | |
| H | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| H | ASP189 | |
| Chain | Residue | Details |
| H | ASN175 | |
| L | GLU7 | |
| L | GLU14 | |
| L | GLU16 | |
| L | GLU20 | |
| L | GLU25 | |
| L | GLU26 | |
| L | GLU29 | |
| L | GLU35 | |
| Chain | Residue | Details |
| L | GLU19 | |
| Chain | Residue | Details |
| L | ASP63 | |
| Chain | Residue | Details |
| L | SER52 | |
| Chain | Residue | Details |
| L | SER60 | |
| Chain | Residue | Details |
| L | ASN145 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | ASP102 | |
| H | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | SER195 | |
| H | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | SER195 | |
| H | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | ASP102 | |
| H | SER195 | |
| H | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | ASP102 | |
| H | SER195 | |
| H | HIS57 | |
| H | GLY196 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| H | ASP102 | |
| H | SER195 | |
| H | GLY193 | |
| H | HIS57 | |
