1O58
Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.80 A resolution
Replaces: 1J6NFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| A | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| C | 0004124 | molecular_function | cysteine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006535 | biological_process | cysteine biosynthetic process from serine |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| D | 0004124 | molecular_function | cysteine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006535 | biological_process | cysteine biosynthetic process from serine |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1401 |
| Chain | Residue |
| A | LYS35 |
| A | THR60 |
| A | SER61 |
| A | ASN63 |
| A | MET64 |
| A | GLN132 |
| A | HOH1490 |
| A | HOH1503 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1402 |
| Chain | Residue |
| A | VAL165 |
| A | GLY166 |
| A | THR167 |
| A | GLY168 |
| A | GLY169 |
| A | THR170 |
| A | HOH1409 |
| A | HOH1421 |
| A | HOH1446 |
| A | LYS35 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1403 |
| Chain | Residue |
| B | LYS35 |
| B | GLY166 |
| B | THR167 |
| B | GLY168 |
| B | GLY169 |
| B | THR170 |
| B | HOH1406 |
| B | HOH1407 |
| B | HOH1410 |
| B | HOH1494 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1404 |
| Chain | Residue |
| B | LYS35 |
| B | THR60 |
| B | SER61 |
| B | ASN63 |
| B | MET64 |
| B | GLN132 |
| B | HOH1432 |
| B | HOH1575 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 C 1405 |
| Chain | Residue |
| C | LYS35 |
| C | VAL165 |
| C | GLY166 |
| C | THR167 |
| C | GLY168 |
| C | GLY169 |
| C | THR170 |
| C | HOH1409 |
| C | HOH1411 |
| C | HOH1421 |
| C | HOH1465 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 1406 |
| Chain | Residue |
| C | LYS35 |
| C | SER61 |
| C | GLY62 |
| C | ASN63 |
| C | MET64 |
| C | GLN132 |
| C | HOH1457 |
| C | HOH1501 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 D 1407 |
| Chain | Residue |
| D | LYS35 |
| D | VAL165 |
| D | GLY166 |
| D | THR167 |
| D | GLY168 |
| D | GLY169 |
| D | THR170 |
| D | HOH1412 |
| D | HOH1418 |
| D | HOH1433 |
| D | HOH1500 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 1408 |
| Chain | Residue |
| D | LYS35 |
| D | THR60 |
| D | SER61 |
| D | ASN63 |
| D | MET64 |
| D | GLN132 |
| D | HOH1512 |
| D | HOH1538 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEknn.PGgSVKdRpAlfM |
| Chain | Residue | Details |
| A | LYS24-MET42 |
