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1NW6

Structure of the beta class N6-adenine DNA methyltransferase RsrI bound to sinefungin

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0008168molecular_functionmethyltransferase activity
A0008170molecular_functionN-methyltransferase activity
A0009007molecular_functionsite-specific DNA-methyltransferase (adenine-specific) activity
A0009307biological_processDNA restriction-modification system
A0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL A 501
ChainResidue
AASN136
ALEU137
AASN206

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL A 502
ChainResidue
AGLN226
ALYS227
ASER253

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE SFG A 401
ChainResidue
APRO66
APRO67
AHIS223
ATHR225
APHE249
APHE250
AGLY252
AASP271
AALA272
AHOH596
AHOH634
AASP46
ACYS47
AASP65

Functional Information from PROSITE/UniProt
site_idPS00092
Number of Residues7
DetailsN6_MTASE N-6 Adenine-specific DNA methylases signature. IICDPPY
ChainResidueDetails
AILE62-TYR68

226707

PDB entries from 2024-10-30

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