1NPM
NEUROPSIN, A SERINE PROTEASE EXPRESSED IN THE LIMBIC SYSTEM OF MOUSE BRAIN
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0005737 | cellular_component | cytoplasm |
A | 0006508 | biological_process | proteolysis |
A | 0007613 | biological_process | memory |
A | 0008233 | molecular_function | peptidase activity |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0009611 | biological_process | response to wounding |
A | 0030141 | cellular_component | secretory granule |
A | 0043616 | biological_process | keratinocyte proliferation |
A | 0048812 | biological_process | neuron projection morphogenesis |
A | 0050807 | biological_process | regulation of synapse organization |
A | 0050808 | biological_process | synapse organization |
A | 0097180 | cellular_component | serine protease inhibitor complex |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0005576 | cellular_component | extracellular region |
B | 0005615 | cellular_component | extracellular space |
B | 0005737 | cellular_component | cytoplasm |
B | 0006508 | biological_process | proteolysis |
B | 0007613 | biological_process | memory |
B | 0008233 | molecular_function | peptidase activity |
B | 0008236 | molecular_function | serine-type peptidase activity |
B | 0009611 | biological_process | response to wounding |
B | 0030141 | cellular_component | secretory granule |
B | 0043616 | biological_process | keratinocyte proliferation |
B | 0048812 | biological_process | neuron projection morphogenesis |
B | 0050807 | biological_process | regulation of synapse organization |
B | 0050808 | biological_process | synapse organization |
B | 0097180 | cellular_component | serine protease inhibitor complex |
Functional Information from PDB Data
site_id | ACA |
Number of Residues | 3 |
Details | CATALYTIC TRIAD (ACTIVE SITE). |
Chain | Residue |
A | HIS57 |
A | ASP102 |
A | SER195 |
site_id | ACB |
Number of Residues | 3 |
Details | CATALYTIC TRIAD (ACTIVE SITE). |
Chain | Residue |
B | HIS57 |
B | ASP102 |
B | SER195 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Charge relay system => ECO:0000250 |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
B | HIS57 | |
B | ASP102 | |
B | SER195 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN95 | |
B | ASN95 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | GLY193 | |
B | HIS57 |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 | |
A | GLY196 |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 | |
B | GLY196 |
site_id | CSA7 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |
A | SER214 |
site_id | CSA8 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | GLY193 | |
B | HIS57 | |
B | SER214 |