1NPB

Crystal structure of the fosfomycin resistance protein from transposon Tn2921

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005737	cellular_component	cytoplasm
A	0016740	molecular_function	transferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0004364	molecular_function	glutathione transferase activity
B	0005737	cellular_component	cytoplasm
B	0016740	molecular_function	transferase activity
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
C	0004364	molecular_function	glutathione transferase activity
C	0005737	cellular_component	cytoplasm
C	0016740	molecular_function	transferase activity
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding
D	0004364	molecular_function	glutathione transferase activity
D	0005737	cellular_component	cytoplasm
D	0016740	molecular_function	transferase activity
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding
E	0004364	molecular_function	glutathione transferase activity
E	0005737	cellular_component	cytoplasm
E	0016740	molecular_function	transferase activity
E	0046677	biological_process	response to antibiotic
E	0046872	molecular_function	metal ion binding
F	0004364	molecular_function	glutathione transferase activity
F	0005737	cellular_component	cytoplasm
F	0016740	molecular_function	transferase activity
F	0046677	biological_process	response to antibiotic
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 401

Chain	Residue
A	HIS7
B	HIS67
B	SER97
B	TYR103
B	GLU113
B	ARG122
B	HOH550

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 402

Chain	Residue
A	ARG122
A	ALA125
A	HOH520
A	GLY99
A	HIS115

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 403

Chain	Residue
A	TYR65
A	HIS67
A	TYR103
A	GLU113
A	ARG122
A	HOH555
B	HIS7

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 404

Chain	Residue
C	HIS7
D	TYR65
D	HIS67
D	TYR103
D	GLU113
D	ARG122
D	HOH543

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 405

Chain	Residue
C	GLY99
C	HIS115
C	ARG122

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 406

Chain	Residue
C	HIS67
C	TYR103
C	GLU113
C	ARG122
C	HOH560
D	HIS7

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 407

Chain	Residue
D	GLY99
D	HIS115
D	ARG122

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 F 408

Chain	Residue
E	HIS7
E	THR9
F	TYR65
F	HIS67
F	TYR103
F	GLU113
F	ARG122
F	HOH555

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 409

Chain	Residue
E	HIS115
E	ARG122
E	HOH515

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 410

Chain	Residue
E	TYR65
E	HIS67
E	TYR103
E	GLU113
E	ARG122
F	HIS7
F	THR9

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	VAL58
A	GLU62
A	SER63
A	ASP64
A	HOH526
A	HOH542
B	GOL502

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 502

Chain	Residue
A	GOL501
B	SER63
B	ASP64
B	HOH536
B	HOH539
B	HOH546
B	HOH552

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 503

Chain	Residue
C	SER63
C	ASP64
C	HOH533
C	HOH541
D	ARG55
D	GOL504

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D 504

Chain	Residue
C	GOL503
D	GLU62
D	SER63
D	ASP64
D	HOH526
D	HOH527
D	HOH545

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 505

Chain	Residue
E	GLU62
E	SER63
E	ASP64
E	HOH535
E	HOH545
F	GOL506
F	HOH524

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL F 506

Chain	Residue
E	GOL505
F	SER63
F	ASP64
F	HOH528

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 507

Chain	Residue
F	LEU15
F	GLN16
F	ARG33
F	ASN35
F	HOH515

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	678
Details	Domain: {"description":"VOC","evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
A	GLU113

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
B	GLU113

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
C	GLU113

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
D	GLU113

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
E	GLU113

---

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
F	GLU113

---