Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1NPB

Crystal structure of the fosfomycin resistance protein from transposon Tn2921

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005737	cellular_component	cytoplasm
A	0016740	molecular_function	transferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0004364	molecular_function	glutathione transferase activity
B	0005737	cellular_component	cytoplasm
B	0016740	molecular_function	transferase activity
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
C	0004364	molecular_function	glutathione transferase activity
C	0005737	cellular_component	cytoplasm
C	0016740	molecular_function	transferase activity
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding
D	0004364	molecular_function	glutathione transferase activity
D	0005737	cellular_component	cytoplasm
D	0016740	molecular_function	transferase activity
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding
E	0004364	molecular_function	glutathione transferase activity
E	0005737	cellular_component	cytoplasm
E	0016740	molecular_function	transferase activity
E	0046677	biological_process	response to antibiotic
E	0046872	molecular_function	metal ion binding
F	0004364	molecular_function	glutathione transferase activity
F	0005737	cellular_component	cytoplasm
F	0016740	molecular_function	transferase activity
F	0046677	biological_process	response to antibiotic
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 401

Chain	Residue
A	HIS7
B	HIS67
B	SER97
B	TYR103
B	GLU113
B	ARG122
B	HOH550

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 402

Chain	Residue
A	ARG122
A	ALA125
A	HOH520
A	GLY99
A	HIS115

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 403

Chain	Residue
A	TYR65
A	HIS67
A	TYR103
A	GLU113
A	ARG122
A	HOH555
B	HIS7

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 404

Chain	Residue
C	HIS7
D	TYR65
D	HIS67
D	TYR103
D	GLU113
D	ARG122
D	HOH543

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 405

Chain	Residue
C	GLY99
C	HIS115
C	ARG122

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 406

Chain	Residue
C	HIS67
C	TYR103
C	GLU113
C	ARG122
C	HOH560
D	HIS7

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 407

Chain	Residue
D	GLY99
D	HIS115
D	ARG122

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 F 408

Chain	Residue
E	HIS7
E	THR9
F	TYR65
F	HIS67
F	TYR103
F	GLU113
F	ARG122
F	HOH555

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 409

Chain	Residue
E	HIS115
E	ARG122
E	HOH515

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 410

Chain	Residue
E	TYR65
E	HIS67
E	TYR103
E	GLU113
E	ARG122
F	HIS7
F	THR9

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	VAL58
A	GLU62
A	SER63
A	ASP64
A	HOH526
A	HOH542
B	GOL502

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 502

Chain	Residue
A	GOL501
B	SER63
B	ASP64
B	HOH536
B	HOH539
B	HOH546
B	HOH552

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 503

Chain	Residue
C	SER63
C	ASP64
C	HOH533
C	HOH541
D	ARG55
D	GOL504

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D 504

Chain	Residue
C	GOL503
D	GLU62
D	SER63
D	ASP64
D	HOH526
D	HOH527
D	HOH545

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 505

Chain	Residue
E	GLU62
E	SER63
E	ASP64
E	HOH535
E	HOH545
F	GOL506
F	HOH524

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL F 506

Chain	Residue
E	GOL505
F	SER63
F	ASP64
F	HOH528

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 507

Chain	Residue
F	LEU15
F	GLN16
F	ARG33
F	ASN35
F	HOH515

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING:

Chain	Residue	Details
A	HIS7
D	HIS7
D	HIS67
D	GLU113
E	HIS7
E	HIS67
E	GLU113
F	HIS7
F	HIS67
F	GLU113
A	HIS67
A	GLU113
B	HIS7
B	HIS67
B	GLU113
C	HIS7
C	HIS67
C	GLU113

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
A	GLU113

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
B	GLU113

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
C	GLU113

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
D	GLU113

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
E	GLU113

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1fro

Chain	Residue	Details
F	GLU113

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)