1NP3

Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0005829	cellular_component	cytosol
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0050661	molecular_function	NADP binding
A	1901705	biological_process	L-isoleucine biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0005829	cellular_component	cytosol
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0050661	molecular_function	NADP binding
B	1901705	biological_process	L-isoleucine biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0005829	cellular_component	cytosol
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0050661	molecular_function	NADP binding
C	1901705	biological_process	L-isoleucine biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0004455	molecular_function	ketol-acid reductoisomerase activity
D	0005829	cellular_component	cytosol
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0050661	molecular_function	NADP binding
D	1901705	biological_process	L-isoleucine biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	720
Details	Domain: {"description":"KARI N-terminal Rossmann","evidences":[{"source":"PROSITE-ProRule","id":"PRU01197","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12691757","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	580
Details	Domain: {"description":"KARI C-terminal knotted","evidences":[{"source":"PROSITE-ProRule","id":"PRU01198","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12691757","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
A	GLU230

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
B	GLU230

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
C	GLU230

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
D	GLU230

---