1NP3

Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0050661	molecular_function	NADP binding
B	0000287	molecular_function	magnesium ion binding
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050661	molecular_function	NADP binding
C	0000287	molecular_function	magnesium ion binding
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0005829	cellular_component	cytosol
C	0008652	biological_process	amino acid biosynthetic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0050661	molecular_function	NADP binding
D	0000287	molecular_function	magnesium ion binding
D	0004455	molecular_function	ketol-acid reductoisomerase activity
D	0005829	cellular_component	cytosol
D	0008652	biological_process	amino acid biosynthetic process
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0050661	molecular_function	NADP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435

Chain	Residue	Details
A	HIS107
B	HIS107
C	HIS107
D	HIS107

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site_id	SWS_FT_FI2
Number of Residues	44
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435

Chain	Residue	Details
A	TYR24
A	GLU230
A	SER251
B	TYR24
B	ARG47
B	SER50
B	THR52
B	ASP82
B	GLY133
B	ASP190
B	GLU194
A	ARG47
B	GLU226
B	GLU230
B	SER251
C	TYR24
C	ARG47
C	SER50
C	THR52
C	ASP82
C	GLY133
C	ASP190
A	SER50
C	GLU194
C	GLU226
C	GLU230
C	SER251
D	TYR24
D	ARG47
D	SER50
D	THR52
D	ASP82
D	GLY133
A	THR52
D	ASP190
D	GLU194
D	GLU226
D	GLU230
D	SER251
A	ASP82
A	GLY133
A	ASP190
A	GLU194
A	GLU226

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
A	GLU230

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
B	GLU230

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site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
C	GLU230

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site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1yve

Chain	Residue	Details
D	GLU230

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