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1NHJ

Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one sodium

Functional Information from GO Data
ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0006298biological_processmismatch repair
A0016887molecular_functionATP hydrolysis activity
A0030983molecular_functionmismatched DNA binding
A0032300cellular_componentmismatch repair complex
A0140664molecular_functionATP-dependent DNA damage sensor activity
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 390
ChainResidue
AALA71
AALA73
AALA76
AGLY96
APRO100
AANP380

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 370
ChainResidue
AHOH436
AASN33
AANP380
AHOH402

site_idAC3
Number of Residues28
DetailsBINDING SITE FOR RESIDUE ANP A 380
ChainResidue
AILE3
AGLU29
AASN33
AALA37
AASP58
AGLY62
AILE63
AALA71
ATHR77
ASER78
ALYS79
AGLY93
APHE94
AARG95
AGLY96
AGLU97
AALA98
ALEU99
APRO100
ATHR143
ALYS307
AMG370
ANA390
AHOH397
AHOH435
AHOH437
AHOH446
AHOH516

Functional Information from PROSITE/UniProt
site_idPS00058
Number of Residues7
DetailsDNA_MISMATCH_REPAIR_1 DNA mismatch repair proteins mutL / hexB / PMS1 signature. GFRGEAL
ChainResidueDetails
AGLY93-LEU99

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PDB entries from 2024-11-13

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