Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004802 | molecular_function | transketolase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004802 | molecular_function | transketolase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 681 |
| Chain | Residue |
| A | ASP157 |
| A | ASN187 |
| A | ILE189 |
| A | TPP682 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 681 |
| Chain | Residue |
| B | ASP157 |
| B | ASN187 |
| B | ILE189 |
| B | TPP682 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE E4P A 900 |
| Chain | Residue |
| A | HIS263 |
| A | GLY264 |
| A | TPP682 |
| B | SER386 |
| B | HIS469 |
| B | ASP477 |
| B | ARG528 |
| A | HIS30 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TPP A 682 |
| Chain | Residue |
| A | HIS69 |
| A | GLY116 |
| A | PRO117 |
| A | LEU118 |
| A | GLY156 |
| A | ASP157 |
| A | GLY158 |
| A | GLU162 |
| A | ASN187 |
| A | ILE189 |
| A | THR190 |
| A | ILE191 |
| A | HIS263 |
| A | CA681 |
| A | E4P900 |
| A | HOH932 |
| B | ASP382 |
| B | ILE416 |
| B | GLU418 |
| B | PHE445 |
| B | TYR448 |
| B | HIS481 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE E4P B 900 |
| Chain | Residue |
| A | SER386 |
| A | HIS469 |
| A | ASP477 |
| A | ARG528 |
| A | HOH1057 |
| B | HIS30 |
| B | ILE191 |
| B | HIS263 |
| B | TPP682 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE TPP B 682 |
| Chain | Residue |
| A | ASP382 |
| A | GLU418 |
| A | PHE445 |
| A | TYR448 |
| B | ALA33 |
| B | HIS69 |
| B | GLY116 |
| B | PRO117 |
| B | LEU118 |
| B | GLY158 |
| B | GLU162 |
| B | ASN187 |
| B | ILE189 |
| B | THR190 |
| B | ILE191 |
| B | ILE250 |
| B | HIS263 |
| B | CA681 |
| B | E4P900 |
| B | HOH923 |
Functional Information from PROSITE/UniProt
| site_id | PS00801 |
| Number of Residues | 21 |
| Details | TRANSKETOLASE_1 Transketolase signature 1. RilaVDtvskanSGHPGapLG |
| Chain | Residue | Details |
| A | ARG16-GLY36 | |
| site_id | PS00802 |
| Number of Residues | 17 |
| Details | TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPIEtlAhfR |
| Chain | Residue | Details |
| A | GLY475-ARG491 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | HIS419 | |
| B | HIS419 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PRO31 | |
| B | GLY158 | |
| B | THR190 | |
| B | LYS360 | |
| B | ASN387 | |
| B | ASP470 | |
| B | GLY478 | |
| B | GLN529 | |
| A | GLY158 | |
| A | THR190 | |
| A | LYS360 | |
| A | ASN387 | |
| A | ASP470 | |
| A | GLY478 | |
| A | GLN529 | |
| B | PRO31 | |
| Chain | Residue | Details |
| A | ALA70 | |
| B | CYS159 | |
| B | LYS188 | |
| B | GLY264 | |
| B | HIS419 | |
| B | VAL446 | |
| A | PRO117 | |
| A | CYS159 | |
| A | LYS188 | |
| A | GLY264 | |
| A | HIS419 | |
| A | VAL446 | |
| B | ALA70 | |
| B | PRO117 | |
| Chain | Residue | Details |
| A | PRO31 | |
| A | GLY264 | |
| B | PRO31 | |
| B | GLY264 | |
| Chain | Residue | Details |
| A | PHE287 | |
| B | PHE287 | |
| Chain | Residue | Details |
| A | GLY336 | |
| B | GLY336 | |
| Chain | Residue | Details |
| A | GLY403 | |
| A | LEU493 | |
| B | GLY403 | |
| B | LEU493 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | PHE648 | |
| B | PHE648 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | SER254 | |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | HIS260 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | SER254 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | GLU418 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | GLU418 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | GLU418 | |
| A | HIS481 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | GLU418 | |
| B | HIS481 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | HIS30 | |
| A | HIS263 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | HIS30 | |
| B | HIS263 | |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | HIS260 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 219 |
| Chain | Residue | Details |
| A | PRO31 | activator, hydrogen bond donor, steric role |
| A | GLY264 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS419 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLN482 | electrostatic stabiliser, hydrogen bond acceptor |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 219 |
| Chain | Residue | Details |
| B | PRO31 | activator, hydrogen bond donor, steric role |
| B | GLY264 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | HIS419 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | GLN482 | electrostatic stabiliser, hydrogen bond acceptor |
