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1N7P

Streptococcus pneumoniae Hyaluronate Lyase W292A/F343V Double Mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005576cellular_componentextracellular region
A0005975biological_processcarbohydrate metabolic process
A0016829molecular_functionlyase activity
A0030246molecular_functioncarbohydrate binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:10716923
ChainResidueDetails
AARG466
AASN516
ALEU525

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1c82
ChainResidueDetails
ATYR408
AASN349
AHIS399

site_idCSA2
Number of Residues3
DetailsAnnotated By Reference To The Literature 1c82
ChainResidueDetails
ATYR408
AARG462
AHIS399

site_idCSA3
Number of Residues3
DetailsAnnotated By Reference To The Literature 1c82
ChainResidueDetails
AARG480
ATYR408
AHIS399

site_idMCSA1
Number of Residues4
DetailsM-CSA 439
ChainResidueDetails
AARG466modifies pKa
AASN516modifies pKa
ALEU525proton shuttle (general acid/base)
AMET579modifies pKa

226707

PDB entries from 2024-10-30

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