1N6P
Crystal Structure of Human Rab5a A30E mutant complex with GppNHp
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 201 |
| Chain | Residue |
| A | SER34 |
| A | THR52 |
| A | GNP200 |
| A | HOH301 |
| A | HOH302 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE GNP A 200 |
| Chain | Residue |
| A | LYS33 |
| A | SER34 |
| A | SER35 |
| A | PHE45 |
| A | HIS46 |
| A | GLU47 |
| A | GLN49 |
| A | SER51 |
| A | THR52 |
| A | GLY78 |
| A | ASN133 |
| A | LYS134 |
| A | ASP136 |
| A | LEU137 |
| A | SER163 |
| A | ALA164 |
| A | LYS165 |
| A | LYS180 |
| A | MG201 |
| A | HOH301 |
| A | HOH302 |
| A | HOH303 |
| A | HOH304 |
| A | HOH333 |
| A | HOH341 |
| A | HOH400 |
| A | SER29 |
| A | GLU30 |
| A | VAL31 |
| A | GLY32 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12433916, ECO:0000269|PubMed:14684892, ECO:0000269|PubMed:15378032, ECO:0000269|PubMed:20534488, ECO:0007744|PDB:1N6H, ECO:0007744|PDB:1N6L, ECO:0007744|PDB:1N6N, ECO:0007744|PDB:1N6O, ECO:0007744|PDB:1N6P, ECO:0007744|PDB:1N6R, ECO:0007744|PDB:1R2Q, ECO:0007744|PDB:1TU3, ECO:0007744|PDB:3MJH |
| Chain | Residue | Details |
| A | GLY27 | |
| A | HIS46 | |
| A | ASP75 | |
| A | ASN133 | |
| A | SER163 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by LRRK2 => ECO:0000269|PubMed:29125462 |
| Chain | Residue | Details |
| A | SER84 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32974215 |
| Chain | Residue | Details |
| A | ARG120 |
