Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1N4R

Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004659	molecular_function	prenyltransferase activity
A	0004660	molecular_function	protein farnesyltransferase activity
A	0004661	molecular_function	protein geranylgeranyltransferase activity
A	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
A	0004663	molecular_function	Rab geranylgeranyltransferase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005875	cellular_component	microtubule associated complex
A	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
A	0005965	cellular_component	protein farnesyltransferase complex
A	0007167	biological_process	enzyme-linked receptor protein signaling pathway
A	0007323	biological_process	peptide pheromone maturation
A	0008017	molecular_function	microtubule binding
A	0008270	molecular_function	zinc ion binding
A	0008284	biological_process	positive regulation of cell population proliferation
A	0008318	molecular_function	protein prenyltransferase activity
A	0010698	molecular_function	acetyltransferase activator activity
A	0016601	biological_process	Rac protein signal transduction
A	0016740	molecular_function	transferase activity
A	0018342	biological_process	protein prenylation
A	0018343	biological_process	protein farnesylation
A	0018344	biological_process	protein geranylgeranylation
A	0019899	molecular_function	enzyme binding
A	0030971	molecular_function	receptor tyrosine kinase binding
A	0035022	biological_process	positive regulation of Rac protein signal transduction
A	0036094	molecular_function	small molecule binding
A	0042277	molecular_function	peptide binding
A	0043014	molecular_function	alpha-tubulin binding
A	0043066	biological_process	negative regulation of apoptotic process
A	0045787	biological_process	positive regulation of cell cycle
A	0060090	molecular_function	molecular adaptor activity
A	0060632	biological_process	regulation of microtubule-based movement
A	1901363	molecular_function	heterocyclic compound binding
A	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
B	0003824	molecular_function	catalytic activity
B	0004659	molecular_function	prenyltransferase activity
B	0004661	molecular_function	protein geranylgeranyltransferase activity
B	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
B	0005515	molecular_function	protein binding
B	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
B	0008270	molecular_function	zinc ion binding
B	0008284	biological_process	positive regulation of cell population proliferation
B	0008318	molecular_function	protein prenyltransferase activity
B	0016740	molecular_function	transferase activity
B	0018344	biological_process	protein geranylgeranylation
B	0036094	molecular_function	small molecule binding
B	0042277	molecular_function	peptide binding
B	0045787	biological_process	positive regulation of cell cycle
B	0046872	molecular_function	metal ion binding
B	1901363	molecular_function	heterocyclic compound binding
C	0004659	molecular_function	prenyltransferase activity
C	0004660	molecular_function	protein farnesyltransferase activity
C	0004661	molecular_function	protein geranylgeranyltransferase activity
C	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
C	0004663	molecular_function	Rab geranylgeranyltransferase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005875	cellular_component	microtubule associated complex
C	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
C	0005965	cellular_component	protein farnesyltransferase complex
C	0007167	biological_process	enzyme-linked receptor protein signaling pathway
C	0007323	biological_process	peptide pheromone maturation
C	0008017	molecular_function	microtubule binding
C	0008270	molecular_function	zinc ion binding
C	0008284	biological_process	positive regulation of cell population proliferation
C	0008318	molecular_function	protein prenyltransferase activity
C	0010698	molecular_function	acetyltransferase activator activity
C	0016601	biological_process	Rac protein signal transduction
C	0016740	molecular_function	transferase activity
C	0018342	biological_process	protein prenylation
C	0018343	biological_process	protein farnesylation
C	0018344	biological_process	protein geranylgeranylation
C	0019899	molecular_function	enzyme binding
C	0030971	molecular_function	receptor tyrosine kinase binding
C	0035022	biological_process	positive regulation of Rac protein signal transduction
C	0036094	molecular_function	small molecule binding
C	0042277	molecular_function	peptide binding
C	0043014	molecular_function	alpha-tubulin binding
C	0043066	biological_process	negative regulation of apoptotic process
C	0045787	biological_process	positive regulation of cell cycle
C	0060090	molecular_function	molecular adaptor activity
C	0060632	biological_process	regulation of microtubule-based movement
C	1901363	molecular_function	heterocyclic compound binding
C	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
D	0003824	molecular_function	catalytic activity
D	0004659	molecular_function	prenyltransferase activity
D	0004661	molecular_function	protein geranylgeranyltransferase activity
D	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
D	0005515	molecular_function	protein binding
D	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
D	0008270	molecular_function	zinc ion binding
D	0008284	biological_process	positive regulation of cell population proliferation
D	0008318	molecular_function	protein prenyltransferase activity
D	0016740	molecular_function	transferase activity
D	0018344	biological_process	protein geranylgeranylation
D	0036094	molecular_function	small molecule binding
D	0042277	molecular_function	peptide binding
D	0045787	biological_process	positive regulation of cell cycle
D	0046872	molecular_function	metal ion binding
D	1901363	molecular_function	heterocyclic compound binding
E	0004659	molecular_function	prenyltransferase activity
E	0004660	molecular_function	protein farnesyltransferase activity
E	0004661	molecular_function	protein geranylgeranyltransferase activity
E	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
E	0004663	molecular_function	Rab geranylgeranyltransferase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005875	cellular_component	microtubule associated complex
E	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
E	0005965	cellular_component	protein farnesyltransferase complex
E	0007167	biological_process	enzyme-linked receptor protein signaling pathway
E	0007323	biological_process	peptide pheromone maturation
E	0008017	molecular_function	microtubule binding
E	0008270	molecular_function	zinc ion binding
E	0008284	biological_process	positive regulation of cell population proliferation
E	0008318	molecular_function	protein prenyltransferase activity
E	0010698	molecular_function	acetyltransferase activator activity
E	0016601	biological_process	Rac protein signal transduction
E	0016740	molecular_function	transferase activity
E	0018342	biological_process	protein prenylation
E	0018343	biological_process	protein farnesylation
E	0018344	biological_process	protein geranylgeranylation
E	0019899	molecular_function	enzyme binding
E	0030971	molecular_function	receptor tyrosine kinase binding
E	0035022	biological_process	positive regulation of Rac protein signal transduction
E	0036094	molecular_function	small molecule binding
E	0042277	molecular_function	peptide binding
E	0043014	molecular_function	alpha-tubulin binding
E	0043066	biological_process	negative regulation of apoptotic process
E	0045787	biological_process	positive regulation of cell cycle
E	0060090	molecular_function	molecular adaptor activity
E	0060632	biological_process	regulation of microtubule-based movement
E	1901363	molecular_function	heterocyclic compound binding
E	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
F	0003824	molecular_function	catalytic activity
F	0004659	molecular_function	prenyltransferase activity
F	0004661	molecular_function	protein geranylgeranyltransferase activity
F	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
F	0005515	molecular_function	protein binding
F	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
F	0008270	molecular_function	zinc ion binding
F	0008284	biological_process	positive regulation of cell population proliferation
F	0008318	molecular_function	protein prenyltransferase activity
F	0016740	molecular_function	transferase activity
F	0018344	biological_process	protein geranylgeranylation
F	0036094	molecular_function	small molecule binding
F	0042277	molecular_function	peptide binding
F	0045787	biological_process	positive regulation of cell cycle
F	0046872	molecular_function	metal ion binding
F	1901363	molecular_function	heterocyclic compound binding
G	0004659	molecular_function	prenyltransferase activity
G	0004660	molecular_function	protein farnesyltransferase activity
G	0004661	molecular_function	protein geranylgeranyltransferase activity
G	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
G	0004663	molecular_function	Rab geranylgeranyltransferase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005875	cellular_component	microtubule associated complex
G	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
G	0005965	cellular_component	protein farnesyltransferase complex
G	0007167	biological_process	enzyme-linked receptor protein signaling pathway
G	0007323	biological_process	peptide pheromone maturation
G	0008017	molecular_function	microtubule binding
G	0008270	molecular_function	zinc ion binding
G	0008284	biological_process	positive regulation of cell population proliferation
G	0008318	molecular_function	protein prenyltransferase activity
G	0010698	molecular_function	acetyltransferase activator activity
G	0016601	biological_process	Rac protein signal transduction
G	0016740	molecular_function	transferase activity
G	0018342	biological_process	protein prenylation
G	0018343	biological_process	protein farnesylation
G	0018344	biological_process	protein geranylgeranylation
G	0019899	molecular_function	enzyme binding
G	0030971	molecular_function	receptor tyrosine kinase binding
G	0035022	biological_process	positive regulation of Rac protein signal transduction
G	0036094	molecular_function	small molecule binding
G	0042277	molecular_function	peptide binding
G	0043014	molecular_function	alpha-tubulin binding
G	0043066	biological_process	negative regulation of apoptotic process
G	0045787	biological_process	positive regulation of cell cycle
G	0060090	molecular_function	molecular adaptor activity
G	0060632	biological_process	regulation of microtubule-based movement
G	1901363	molecular_function	heterocyclic compound binding
G	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
H	0003824	molecular_function	catalytic activity
H	0004659	molecular_function	prenyltransferase activity
H	0004661	molecular_function	protein geranylgeranyltransferase activity
H	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
H	0005515	molecular_function	protein binding
H	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
H	0008270	molecular_function	zinc ion binding
H	0008284	biological_process	positive regulation of cell population proliferation
H	0008318	molecular_function	protein prenyltransferase activity
H	0016740	molecular_function	transferase activity
H	0018344	biological_process	protein geranylgeranylation
H	0036094	molecular_function	small molecule binding
H	0042277	molecular_function	peptide binding
H	0045787	biological_process	positive regulation of cell cycle
H	0046872	molecular_function	metal ion binding
H	1901363	molecular_function	heterocyclic compound binding
I	0004659	molecular_function	prenyltransferase activity
I	0004660	molecular_function	protein farnesyltransferase activity
I	0004661	molecular_function	protein geranylgeranyltransferase activity
I	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
I	0004663	molecular_function	Rab geranylgeranyltransferase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005875	cellular_component	microtubule associated complex
I	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
I	0005965	cellular_component	protein farnesyltransferase complex
I	0007167	biological_process	enzyme-linked receptor protein signaling pathway
I	0007323	biological_process	peptide pheromone maturation
I	0008017	molecular_function	microtubule binding
I	0008270	molecular_function	zinc ion binding
I	0008284	biological_process	positive regulation of cell population proliferation
I	0008318	molecular_function	protein prenyltransferase activity
I	0010698	molecular_function	acetyltransferase activator activity
I	0016601	biological_process	Rac protein signal transduction
I	0016740	molecular_function	transferase activity
I	0018342	biological_process	protein prenylation
I	0018343	biological_process	protein farnesylation
I	0018344	biological_process	protein geranylgeranylation
I	0019899	molecular_function	enzyme binding
I	0030971	molecular_function	receptor tyrosine kinase binding
I	0035022	biological_process	positive regulation of Rac protein signal transduction
I	0036094	molecular_function	small molecule binding
I	0042277	molecular_function	peptide binding
I	0043014	molecular_function	alpha-tubulin binding
I	0043066	biological_process	negative regulation of apoptotic process
I	0045787	biological_process	positive regulation of cell cycle
I	0060090	molecular_function	molecular adaptor activity
I	0060632	biological_process	regulation of microtubule-based movement
I	1901363	molecular_function	heterocyclic compound binding
I	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
J	0003824	molecular_function	catalytic activity
J	0004659	molecular_function	prenyltransferase activity
J	0004661	molecular_function	protein geranylgeranyltransferase activity
J	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
J	0005515	molecular_function	protein binding
J	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
J	0008270	molecular_function	zinc ion binding
J	0008284	biological_process	positive regulation of cell population proliferation
J	0008318	molecular_function	protein prenyltransferase activity
J	0016740	molecular_function	transferase activity
J	0018344	biological_process	protein geranylgeranylation
J	0036094	molecular_function	small molecule binding
J	0042277	molecular_function	peptide binding
J	0045787	biological_process	positive regulation of cell cycle
J	0046872	molecular_function	metal ion binding
J	1901363	molecular_function	heterocyclic compound binding
K	0004659	molecular_function	prenyltransferase activity
K	0004660	molecular_function	protein farnesyltransferase activity
K	0004661	molecular_function	protein geranylgeranyltransferase activity
K	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
K	0004663	molecular_function	Rab geranylgeranyltransferase activity
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005875	cellular_component	microtubule associated complex
K	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
K	0005965	cellular_component	protein farnesyltransferase complex
K	0007167	biological_process	enzyme-linked receptor protein signaling pathway
K	0007323	biological_process	peptide pheromone maturation
K	0008017	molecular_function	microtubule binding
K	0008270	molecular_function	zinc ion binding
K	0008284	biological_process	positive regulation of cell population proliferation
K	0008318	molecular_function	protein prenyltransferase activity
K	0010698	molecular_function	acetyltransferase activator activity
K	0016601	biological_process	Rac protein signal transduction
K	0016740	molecular_function	transferase activity
K	0018342	biological_process	protein prenylation
K	0018343	biological_process	protein farnesylation
K	0018344	biological_process	protein geranylgeranylation
K	0019899	molecular_function	enzyme binding
K	0030971	molecular_function	receptor tyrosine kinase binding
K	0035022	biological_process	positive regulation of Rac protein signal transduction
K	0036094	molecular_function	small molecule binding
K	0042277	molecular_function	peptide binding
K	0043014	molecular_function	alpha-tubulin binding
K	0043066	biological_process	negative regulation of apoptotic process
K	0045787	biological_process	positive regulation of cell cycle
K	0060090	molecular_function	molecular adaptor activity
K	0060632	biological_process	regulation of microtubule-based movement
K	1901363	molecular_function	heterocyclic compound binding
K	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
L	0003824	molecular_function	catalytic activity
L	0004659	molecular_function	prenyltransferase activity
L	0004661	molecular_function	protein geranylgeranyltransferase activity
L	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
L	0005515	molecular_function	protein binding
L	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
L	0008270	molecular_function	zinc ion binding
L	0008284	biological_process	positive regulation of cell population proliferation
L	0008318	molecular_function	protein prenyltransferase activity
L	0016740	molecular_function	transferase activity
L	0018344	biological_process	protein geranylgeranylation
L	0036094	molecular_function	small molecule binding
L	0042277	molecular_function	peptide binding
L	0045787	biological_process	positive regulation of cell cycle
L	0046872	molecular_function	metal ion binding
L	1901363	molecular_function	heterocyclic compound binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 378

Chain	Residue
B	ASP269
B	CYS271
B	HIS321
M	CYS108
M	GER1108

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 378

Chain	Residue
N	GER1208
D	ASP269
D	CYS271
D	HIS321
N	CYS208

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN F 378

Chain	Residue
F	ASP269
F	CYS271
F	HIS321
O	CYS308
O	GER1308

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN H 378

Chain	Residue
H	ASP269
H	CYS271
H	HIS321
P	CYS408
P	GER1408

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN J 378

Chain	Residue
J	ASP269
J	CYS271
J	HIS321
Q	CYS508
Q	GER1508

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN L 378

Chain	Residue
L	ASP269
L	CYS271
L	HIS321
R	CYS608
R	GER1608

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 801

Chain	Residue
C	ARG287
C	ARG291
C	TYR292
C	HOH922

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 802

Chain	Residue
D	LYS284
D	ILE285
D	PHE286
D	GLN287

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL F 803

Chain	Residue
F	LYS284
F	PHE286
F	GLN287

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL G 804

Chain	Residue
G	ARG253
G	ARG287
G	ARG291
G	TYR292
G	HOH913
G	HOH932

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL H 805

Chain	Residue
H	LYS284
H	ILE285
H	PHE286
H	GLN287

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL J 806

Chain	Residue
J	LYS281
J	LYS284
J	ILE285
J	PHE286
J	GLN287

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL K 807

Chain	Residue
K	ARG287
K	ARG291
K	TYR292
K	HOH986

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 810

Chain	Residue
A	MES901
B	HIS219
B	ARG263
B	LYS266
B	TYR272
B	HOH830
B	HOH833
M	GER1108

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 811

Chain	Residue
C	MES902
D	HIS219
D	ARG263
D	LYS266
D	TYR272
D	HOH823
N	GER1208

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 F 812

Chain	Residue
E	HOH935
F	HIS219
F	ARG263
F	LYS266
F	TYR272
F	HOH843
O	GER1308

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 H 813

Chain	Residue
G	MES904
H	HIS219
H	ARG263
H	LYS266
H	TYR272
H	HOH820
H	HOH828
P	GER1408

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 J 814

Chain	Residue
J	HIS219
J	ARG263
J	LYS266
J	TYR272
J	HOH823
Q	GER1508

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 L 815

Chain	Residue
L	TYR272
L	HOH855
R	GER1608
K	MES906
L	ARG263
L	LYS266

site_id	CC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MES A 901

Chain	Residue
A	LYS164
A	TYR166
A	LYS198
A	ASN199
A	TYR200
A	HIS201
B	GLN212
B	HIS219
B	ARG263
B	SO4810
M	GER1108

site_id	CC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MES C 902

Chain	Residue
C	LYS164
C	TYR166
C	LYS198
C	ASN199
C	TYR200
C	HIS201
D	GLN212
D	HIS219
D	ARG263
D	SO4811

site_id	CC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MES E 903

Chain	Residue
E	LYS164
E	TYR166
E	LYS198
E	ASN199
E	TYR200
E	HIS201
E	HOH935
F	GLN212
F	HIS219
F	ARG263
O	GER1308

site_id	CC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE MES G 904

Chain	Residue
G	LYS164
G	TYR166
G	LYS198
G	ASN199
G	TYR200
G	HIS201
G	HOH931
H	GLN212
H	HIS219
H	ARG263
H	SO4813
P	GER1408

site_id	CC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MES I 905

Chain	Residue
I	LYS164
I	TYR166
I	LYS198
I	ASN199
I	TYR200
I	HIS201
J	GLN212
J	HIS219
J	ARG263

site_id	CC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MES K 906

Chain	Residue
K	LYS164
K	TYR166
K	LYS198
K	ASN199
K	TYR200
K	HIS201
L	GLN212
L	HIS219
L	ARG263
L	SO4815
R	GER1608

site_id	CC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GER M 1108

Chain	Residue
A	MES901
B	ARG173
B	ASP269
B	TYR272
B	TRP275
B	ZN378
B	SO4810
M	CYS108
M	ILE110

site_id	CC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GER N 1208

Chain	Residue
D	ARG173
D	GLN212
D	ASP269
D	TYR272
D	TRP275
D	ZN378
D	SO4811
N	CYS208
N	ILE210

site_id	DC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GER O 1308

Chain	Residue
E	MES903
F	ARG173
F	ASP269
F	TYR272
F	TRP275
F	ZN378
F	SO4812
O	CYS308
O	ILE310

site_id	DC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GER P 1408

Chain	Residue
G	MES904
H	ARG173
H	HIS219
H	ASP269
H	TYR272
H	TRP275
H	ZN378
H	SO4813
P	CYS408
P	ILE410

site_id	DC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GER Q 1508

Chain	Residue
J	ARG173
J	ASP269
J	TYR272
J	TRP275
J	ZN378
J	SO4814
Q	CYS508
Q	ILE510

site_id	DC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GER R 1608

Chain	Residue
K	MES906
L	ARG173
L	GLN212
L	ASP269
L	TYR272
L	TRP275
L	ZN378
L	SO4815
R	CYS608
R	ILE610

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	204
Details	Repeat: {"description":"PFTA 1"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	204
Details	Repeat: {"description":"PFTA 2"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	192
Details	Repeat: {"description":"PFTA 3"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	204
Details	Repeat: {"description":"PFTA 4"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	204
Details	Repeat: {"description":"PFTA 5"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	252
Details	Repeat: {"description":"PFTB 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	246
Details	Repeat: {"description":"PFTB 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	234
Details	Repeat: {"description":"PFTB 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	252
Details	Repeat: {"description":"PFTB 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	66
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14609943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1N4P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	12
Details	Propeptide: {"description":"Removed in mature form","featureId":"PRO_0000281291","evidences":[{"source":"PubMed","id":"27791178","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	6
Details	Modified residue: {"description":"Cysteine methyl ester","evidences":[{"source":"PubMed","id":"27791178","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TB5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	6
Details	Lipidation: {"description":"N6-palmitoyl lysine","evidences":[{"source":"PubMed","id":"29239724","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	6
Details	Lipidation: {"description":"S-farnesyl cysteine","evidences":[{"source":"PubMed","id":"27791178","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24415755","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5TAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TB5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
A	LYS164
B	TYR272

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
C	LYS164
D	TYR272

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
F	TYR272
E	LYS164

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
H	TYR272
G	LYS164

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
J	TYR272
I	LYS164

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
K	LYS164
L	TYR272

site_id	MCSA1
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
A	LYS164	electrostatic stabiliser

site_id	MCSA2
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
C	LYS164	electrostatic stabiliser

site_id	MCSA3
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
E	LYS164	electrostatic stabiliser

site_id	MCSA4
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
G	LYS164	electrostatic stabiliser

site_id	MCSA5
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
I	LYS164	electrostatic stabiliser

site_id	MCSA6
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
K	LYS164	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)