Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1N3L

Crystal structure of a human aminoacyl-tRNA synthetase cytokine

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004812molecular_functionaminoacyl-tRNA ligase activity
A0004831molecular_functiontyrosine-tRNA ligase activity
A0005524molecular_functionATP binding
A0006418biological_processtRNA aminoacylation for protein translation
A0006437biological_processtyrosyl-tRNA aminoacylation
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 A 501
ChainResidue
AHIS49
AHOH2035
AVAL50
AALA51
AGLY217
ALEU218
ATHR219
ALYS231
AHOH2010
AHOH2033

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 502
ChainResidue
AHIS305
APRO306
AGLY307
AASP308
AHOH2199
AHOH2211

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 503
ChainResidue
ALYS26
AARG34
AHOH2066
AHOH2230

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 504
ChainResidue
ALYS282
ATRP283
AHOH2040
AHOH2294

site_idAC5
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL A 601
ChainResidue
AMET214
APRO216
ASER262
ALYS265
AHIS266
AHOH2086
AHOH2101
AHOH2146
AHOH2223

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 602
ChainResidue
AHIS12
AARG16
ASER273

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:25533949, ECO:0007744|PDB:4Q93
ChainResidueDetails
ATYR39
AGLN170
AASP173

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:14671330, ECO:0007744|PDB:4QBT
ChainResidueDetails
ATYR166
AGLN188

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330
ChainResidueDetails
AMET1

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: N-acetylglycine; in Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed => ECO:0000269|Ref.8, ECO:0007744|PubMed:19413330
ChainResidueDetails
AGLY2

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS197
ALYS206

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER205

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon