1MQJ
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | GLU42 |
| A | HIS46 |
| A | HOH510 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HWD A 301 |
| Chain | Residue |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | LEU192 |
| A | GLU193 |
| A | MET196 |
| A | HOH407 |
| A | HOH435 |
| A | HOH494 |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | LEU138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11086992, ECO:0000269|PubMed:16483599, ECO:0007744|PDB:1FTJ, ECO:0007744|PDB:2CMO |
| Chain | Residue | Details |
| A | PRO89 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:8848293 |
| Chain | Residue | Details |
| A | SER150 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKG => ECO:0000269|PubMed:8848293 |
| Chain | Residue | Details |
| A | SER184 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 |
