Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003905 | molecular_function | alkylbase DNA N-glycosylase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006285 | biological_process | base-excision repair, AP site formation |
| A | 0006307 | biological_process | DNA alkylation repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008725 | molecular_function | DNA-3-methyladenine glycosylase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0032131 | molecular_function | alkylated DNA binding |
| A | 0043916 | molecular_function | DNA-7-methylguanine glycosylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003905 | molecular_function | alkylbase DNA N-glycosylase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006281 | biological_process | DNA repair |
| B | 0006284 | biological_process | base-excision repair |
| B | 0006285 | biological_process | base-excision repair, AP site formation |
| B | 0006307 | biological_process | DNA alkylation repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008725 | molecular_function | DNA-3-methyladenine glycosylase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0032131 | molecular_function | alkylated DNA binding |
| B | 0043916 | molecular_function | DNA-7-methylguanine glycosylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 283 |
| Chain | Residue |
| A | GLN85 |
| A | CYS86 |
| A | ASN87 |
| A | ILE90 |
| A | TRP263 |
| A | TYR266 |
| A | HOH306 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 283 |
| Chain | Residue |
| B | ASN87 |
| B | ILE90 |
| B | VAL91 |
| B | TRP263 |
| B | TYR266 |
| B | HOH380 |
| B | GLN85 |
| B | CYS86 |
Functional Information from PROSITE/UniProt
| site_id | PS00516 |
| Number of Residues | 25 |
| Details | ALKYLBASE_DNA_GLYCOS Alkylbase DNA glycosidases alkA family signature. GIGrWTAnYFaLrgwqakdvFlpDD |
| Chain | Residue | Details |
| A | GLY214-ASP238 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Determinant for substrate specificity and/or activity"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1diz |
| Chain | Residue | Details |
| A | TRP272 | |
| A | ASP238 | |
| A | TYR222 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1diz |
| Chain | Residue | Details |
| B | TRP272 | |
| B | ASP238 | |
| B | TYR222 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 313 |
| Chain | Residue | Details |
| A | TRP218 | electrostatic stabiliser, van der waals interaction |
| A | TYR222 | electrostatic stabiliser, van der waals interaction |
| A | ASP238 | attractive charge-charge interaction, electrostatic stabiliser, promote heterolysis |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 313 |
| Chain | Residue | Details |
| B | TRP218 | electrostatic stabiliser, van der waals interaction |
| B | TYR222 | electrostatic stabiliser, van der waals interaction |
| B | ASP238 | attractive charge-charge interaction, electrostatic stabiliser, promote heterolysis |
