1MPF

STRUCTURAL AND FUNCTIONAL ALTERATIONS OF A COLICIN RESISTANT MUTANT OF OMPF-PORIN FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001530	molecular_function	lipopolysaccharide binding
A	0005216	molecular_function	monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0008289	molecular_function	lipid binding
A	0009279	cellular_component	cell outer membrane
A	0015031	biological_process	protein transport
A	0015288	molecular_function	porin activity
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034702	cellular_component	monoatomic ion channel complex
A	0042802	molecular_function	identical protein binding
A	0042912	molecular_function	colicin transmembrane transporter activity
A	0043213	biological_process	bacteriocin transport
A	0046930	cellular_component	pore complex
A	0070207	biological_process	protein homotrimerization
A	0097718	molecular_function	disordered domain specific binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE C8E A 341

Chain	Residue
A	LEU158
A	GLY173

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE C8E A 342

Chain	Residue
A	VAL334

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE C8E A 344

Chain	Residue
A	TYR313

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE C8E A 346

Chain	Residue
A	LEU147
A	VAL148
A	ILE178
A	TYR191
A	C8E349

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE C8E A 349

Chain	Residue
A	TRP214
A	C8E346

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE C8E A 353

Chain	Residue
A	ILE273

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE C8E A 354

Chain	Residue
A	ILE273
A	VAL297

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Functional Information from PROSITE/UniProt

site_id	PS00576
Number of Residues	17
Details	GRAM_NEG_PORIN General diffusion Gram-negative porins signature. FevGatYyFnKnmSTYV

Chain	Residue	Details
A	PHE295-VAL311

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	170
Details	Transmembrane: {"description":"Beta stranded"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	14
Details	Topological domain: {"description":"Periplasmic"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	126
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

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