1MO0
Structural Genomics Of Caenorhabditis Elegans: Triose Phosphate Isomerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0008340 | biological_process | determination of adult lifespan |
| A | 0008929 | molecular_function | methylglyoxal synthase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0030016 | cellular_component | myofibril |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0008340 | biological_process | determination of adult lifespan |
| B | 0008929 | molecular_function | methylglyoxal synthase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0030016 | cellular_component | myofibril |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 906 |
| Chain | Residue |
| A | ASN10 |
| A | LYS12 |
| A | HIS94 |
| A | GLU164 |
| A | LEU229 |
| A | VAL230 |
| A | GLY231 |
| A | SO4901 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 907 |
| Chain | Residue |
| B | LYS12 |
| B | HIS94 |
| B | GLU164 |
| B | LEU229 |
| B | VAL230 |
| B | GLY231 |
| B | SO4902 |
| B | ASN10 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 A 901 |
| Chain | Residue |
| A | LYS12 |
| A | GLU164 |
| A | ALA168 |
| A | ILE169 |
| A | GLY170 |
| A | SER210 |
| A | GLY231 |
| A | GLY232 |
| A | ACT906 |
| A | HOH931 |
| A | HOH936 |
| A | HOH978 |
| A | HOH996 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 B 902 |
| Chain | Residue |
| B | LYS12 |
| B | GLU164 |
| B | ALA168 |
| B | ILE169 |
| B | GLY170 |
| B | SER210 |
| B | GLY231 |
| B | GLY232 |
| B | ACT907 |
| B | HOH912 |
| B | HOH922 |
| B | HOH952 |
| B | HOH988 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 903 |
| Chain | Residue |
| A | THR25 |
| A | ASN28 |
| A | HOH1018 |
| A | HOH1054 |
| A | HOH1055 |
| A | HOH1058 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 904 |
| Chain | Residue |
| A | ARG133 |
| A | GLN179 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 905 |
| Chain | Residue |
| B | ARG133 |
| B | GLN179 |
| B | HOH1094 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA162-GLY172 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Electrophile => ECO:0000255|PROSITE-ProRule:PRU10127 |
| Chain | Residue | Details |
| A | HIS94 | |
| B | HIS94 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10127 |
| Chain | Residue | Details |
| A | GLU164 | |
| B | GLU164 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10127 |
| Chain | Residue | Details |
| A | ASN10 | |
| A | LYS12 | |
| B | ASN10 | |
| B | LYS12 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| A | ASN10 | |
| A | GLU164 | |
| A | GLY170 | |
| A | HIS94 | |
| A | LYS12 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| B | ASN10 | |
| B | GLU164 | |
| B | GLY170 | |
| B | HIS94 | |
| B | LYS12 |
