Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | RSS269 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 3 |
| Chain | Residue |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH313 |
| A | HOH369 |
| A | ASP158 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 4 |
| Chain | Residue |
| A | ASP175 |
| A | GLY176 |
| A | GLY178 |
| A | THR180 |
| A | ASP198 |
| A | GLU201 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1 |
| Chain | Residue |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| B | RSS269 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | HIS168 |
| B | ASP170 |
| B | HIS183 |
| B | HIS196 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 3 |
| Chain | Residue |
| B | ASP158 |
| B | GLY190 |
| B | GLY192 |
| B | ASP194 |
| B | HOH341 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 4 |
| Chain | Residue |
| B | ASP175 |
| B | GLY176 |
| B | GLY178 |
| B | THR180 |
| B | ASP198 |
| B | GLU201 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE RSS A 269 |
| Chain | Residue |
| A | ZN1 |
| A | ASN179 |
| A | LEU181 |
| A | ALA182 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| A | HIS228 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | HOH318 |
| B | PRO232 |
| B | ASN242 |
| site_id | BC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE RSS B 269 |
| Chain | Residue |
| A | PRO232 |
| A | ASN242 |
| B | ZN1 |
| B | ASN179 |
| B | LEU181 |
| B | ALA182 |
| B | HIS218 |
| B | GLU219 |
| B | HIS222 |
| B | HIS228 |
| B | PRO238 |
| B | THR239 |
| B | TYR240 |
| B | HOH352 |
| B | HOH353 |
| B | HOH355 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. AATHELGHSL |
| Chain | Residue | Details |
| A | ALA215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | MET236 | |
| A | GLU219 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | MET236 | |
| B | GLU219 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU219 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLU219 | |
