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1MK1

Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme

Functional Information from GO Data
ChainGOidnamespacecontents
A0005829cellular_componentcytosol
A0006753biological_processnucleoside phosphate metabolic process
A0016787molecular_functionhydrolase activity
A0019693biological_processribose phosphate metabolic process
A0030145molecular_functionmanganese ion binding
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE APR A 208
ChainResidue
AILE19
AGLY116
AGLU120
AASN166
AILE168
AHOH212
AHOH229
AHOH233
AHOH240
AHOH277
AHOH284
ATHR36
AHOH289
AHOH290
AHOH291
AARG37
AGLU38
AALA45
AARG64
AGLY77
ALEU78
APRO115

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1mqw
ChainResidueDetails
AARG64

site_idMCSA1
Number of Residues4
DetailsM-CSA 823
ChainResidueDetails
AARG64electrostatic stabiliser
AALA76metal ligand
AGLU93metal ligand
AGLU97metal ligand

247536

PDB entries from 2026-01-14

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