1MJL

METHIONINE REPRESSOR MUTANT (Q44K) COMPLEX WITH THE COREPRESSOR SAM (S-ADENOSYL METHIONINE) FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006555	biological_process	methionine metabolic process
A	0009086	biological_process	methionine biosynthetic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006555	biological_process	methionine metabolic process
B	0009086	biological_process	methionine biosynthetic process
B	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SAM A 200

Chain	Residue
A	ALA1
B	ALA60
B	HIS63
B	LEU70
B	HOH453
A	PHE61
A	HIS63
A	ALA64
A	PHE65
B	GLU39
B	ARG43
B	LEU56
B	GLU59

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SAM B 400

Chain	Residue
A	GLU39
A	ARG43
A	LEU56
A	GLU59
A	HIS63
A	PRO71
B	PHE61
B	HIS63
B	ALA64
B	PHE65
B	GLY67

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