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1MFG

The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor

Functional Information from GO Data
ChainGOidnamespacecontents
A0005176molecular_functionErbB-2 class receptor binding
A0007165biological_processsignal transduction
A0032088biological_processnegative regulation of NF-kappaB transcription factor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues89
DetailsDomain: {"description":"PDZ","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsModified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"17554007","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27134172","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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